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Clinical Trials/NCT06378762
NCT06378762
Active, not recruiting
Not Applicable

Interference of Endurance Training on Strength Development and Neuromuscular Adaptations

University of Lisbon1 site in 1 country30 target enrollmentApril 1, 2022
ConditionsExercise

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Exercise
Sponsor
University of Lisbon
Enrollment
30
Locations
1
Primary Endpoint
H-reflex excitability
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

This study aims to find out if performing combined strength and endurance exercise in the same program (called concurrent training-CT) leads to similar long-term improvements in neuromuscular function as doing each type of exercise separately. The main questions it seeks to answer are:

Does performing CT result in similar improvements in strength and power as doing just strength training? Does performing CT result in similar improvements in cardiorespiratory fitness as doing just endurance training? Are neuromuscular adaptations similar between CT and just strength training? Researchers will compare the results between three groups: the CT group, the endurance training group (E), and the strength training group (S) to answer these questions.

Detailed Description

This study looks at how different types of exercise affect neuromuscular and cardiorespiratory improvements over time. It aims to see how combining strength and endurance training (concurrent training - CT) affects neuromuscular and cardiorespiratory adaptations compared to doing just strength or endurance training. Participants who regularly do both types of exercise will be split into three groups: Concurrent training (CT), endurance training (E), or strength training (S) and will be involved in 11 weeks of supervised training, three days a week: Endurance training involves 30 minutes of continuous running, three days a week, at an intensity corresponding to the heavy domain (between the first and second ventilatory threshold) Strength training includes weightlifting three days a week, focusing on building both strength and power. Concurrent training incorporates both strength and endurance exercises in the same session, three days a week, with strength training being executed prior to endurance training. Researchers will collect data at three time-points during the 11 weeks: before starting the program (Baseline), at the end of week 5 (Week 5), and at the end of the program (Week 11). Measurements include lower-body strength and power, aerobic capacity, nerve evoked responses, and muscle structure if the quadriceps femoris. Researchers will then compare the CT, E, and S groups at each measurement point to see which type of training elicited the best adaptations for the different neuromuscular and cardiorespiratory outcomes.

Registry
clinicaltrials.gov
Start Date
April 1, 2022
End Date
July 30, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Miguel Gomes

Invited Assistant Professor

University of Lisbon

Eligibility Criteria

Inclusion Criteria

  • Active training status (strength and endurance (running) exercise at least 2 times per week over the last three months prior to inclusion in the study)

Exclusion Criteria

  • Active smoking status
  • Orthopedic injuries
  • On medication
  • Known cardiovascular or respiratory disease

Outcomes

Primary Outcomes

H-reflex excitability

Time Frame: Baseline, Week 5, Week 11

Using percutaneous electrostimulation of the tibial nerve, spinal reflex excitability will be explored by assessing H-reflex evoked responses

Lower Body Muscle Power

Time Frame: Baseline, Week 5, Week 11

Lower body muscle power in watts will be assessed during countermovement jumps

Maximal Isometric Strength

Time Frame: Baseline, Week 5, Week 11

Maximal voluntary isometric strength of the plantarflexors and leg press exercise in Newtons

Muscle fascicle length

Time Frame: Baseline, Week 5, Week 11

Fascicle length of the vastus lateralis muscles in centimeters

Muscle fascicle pennation angle

Time Frame: Baseline, Week 5, Week 11

Pennation angle of the vastus laterais fascicles, in degrees

V-wave

Time Frame: Baseline, Week 5, Week 11

Using percutaneous electrostimulation of the tibial nerve, neural drive to the active muscle will be assessed by measuring V-wave amplitudes

Muscle thickenss

Time Frame: Baseline, Week 5, Week 11

Muscle thickenss of the vastus lateralis, in centimeters

Maximal Dynamic Strength

Time Frame: Baseline, Week 5, Week 11

Maximal dynamic strength on the back squat exercise in kilograms lifted

Surface EMG

Time Frame: Baseline, Week 5, Week 11

Using surface electromyography (EMG), the muscle activation of the plantarflexors muscles will me assessed, as well as the quadriceps femoris during the leg press and back squat exercise

Study Sites (1)

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