In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation

Not Applicable

Completed

• Conditions: Lung Diseases; COPD; Respiratory Diseases; Cystic Fibrosis; Asthma

• Registration Number: NCT02084043
• Lead Sponsor: University Hospital St Luc, Brussels

Brief Summary

Using an adult lung bench model of non invasive ventilation, the aim of the study is to compare an experimental system of breath-synchronized vibrating mesh nebulizer to a conventional vibrating mesh nebulizer during non invasive ventilation in terms of inhaled and lost doses.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-03
• Study First Submitted: 2014-03-08
• Study First Submitted QC: 2014-03-08
• Study First Posted: 2014-03-11
• Status Verified: 2015-06
• Primary Completion: 2015-06
• Study Completion: 2015-06
• Last Update Submitted: 2015-06-05
• Last Update Posted: 2015-06-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 3

Inclusion Criteria

• Not applicable (in vitro study)

Exclusion Criteria

• hypersensitivity (allergic) reactions to aminoglycosides

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
Inhaled dose	after 24 hours	The inhaled dose assessed by residual gravimetric method

Secondary Outcome Measures

Name	Time	Method
Expiratory wasted dose	after 24 hours	The dose expelled in the ambient air through the exhalation port assessed by residual gravimetric method

Trial Locations

Locations (1)

University Hospital St Luc; 🇧🇪 Brussels, Belgium