MedPath

Episodic Future Thinking and Future Thinking Priming for Smoking Cessation

Not Applicable
Terminated
Conditions
Tobacco-Related Carcinoma
Interventions
Behavioral: Behavioral Intervention
Other: Informational Intervention
Other: Telephone-Based Intervention
Registration Number
NCT04297332
Lead Sponsor
Roswell Park Cancer Institute
Brief Summary

This trial studies the main and interactive effects of episodic future thinking and future thinking priming tasks on helping participants to quit smoking. Episodic future thinking and future thinking priming tasks may decrease delay discounting rates and reduce relapse to smoking and help participants quit smoking.

Detailed Description

PRIMARY OBJECTIVE:

I. To quantify the main and interactive effects of the episodic future thinking (EFT) and future thinking priming (FTP) tasks on delay discounting rate, latency to relapse, and multiple abstinence and self-regulation measures among smokers (n=76) who call a busy Quitline to quit smoking.

OUTLINE: Participants are randomized to 1 of 4 arms.

ARM I: Participants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.

ARM II: Participants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or control future thinking priming task once per week for 12 weeks, alternating every week between tasks.

ARM III: Participants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.

ARM IV: Participants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or control future thinking priming tasks once per week for 12 weeks, alternating every week between tasks.

Recruitment & Eligibility

Status
TERMINATED
Sex
All
Target Recruitment
26
Inclusion Criteria
  • Smoke >= 8 cigarettes daily
  • Planning to quit in the next 14 days
  • No regular use of other tobacco products
  • Access to the internet
  • In possession of a smartphone with text messaging capabilities
  • In possession of an email address accessible at least every other day
Exclusion Criteria
  • Unable or unwilling to provide consent
  • Unable to provide data to the research team after the quit date
  • Current use of bupropion or varenicline
  • Drinking >= 20 alcoholic drinks per week
  • Use of drugs of abuse in the past 30 days
  • Living in the same household as a participant already enrolled in this study

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Arm && Interventions
GroupInterventionDescription
Arm III (control EFT, active FTP)Nicotine ReplacementParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm IV (control EFT, control TFP)Nicotine ReplacementParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or control future thinking priming tasks once per week for 12 weeks, alternating every week between tasks.
Arm II (active EFT, control FTP)Informational InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or control future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm III (control EFT, active FTP)Behavioral InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm I (active EFT, active FTP)Behavioral InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm II (active EFT, control FTP)Behavioral InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or control future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm II (active EFT, control FTP)Nicotine ReplacementParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or control future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm III (control EFT, active FTP)Informational InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm IV (control EFT, control TFP)Behavioral InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or control future thinking priming tasks once per week for 12 weeks, alternating every week between tasks.
Arm IV (control EFT, control TFP)Informational InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or control future thinking priming tasks once per week for 12 weeks, alternating every week between tasks.
Arm I (active EFT, active FTP)Informational InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm III (control EFT, active FTP)Telephone-Based InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm I (active EFT, active FTP)Telephone-Based InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or active future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm II (active EFT, control FTP)Telephone-Based InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete an active episodic future thinking or control future thinking priming task once per week for 12 weeks, alternating every week between tasks.
Arm IV (control EFT, control TFP)Telephone-Based InterventionParticipants are provided with Forever Free relapse prevention booklets and receive a 2-week supply of nicotine patches, gum, or lozenges. Participants also receive 1 proactive coaching call within 24 hours of quit date. Beginning on the quit date, participants complete a control episodic future thinking or control future thinking priming tasks once per week for 12 weeks, alternating every week between tasks.
Primary Outcome Measures
NameTimeMethod
Latency to relapseBaseline, assessed up to 12 weeks

Will be assessed with the Timeline Follow-Back procedure administered by telephone. Analyzed using generalized mixed models.

Change in Delay discounting rateBaseline, and 4 and 12 weeks after quit date

Assessed with the 5-Trial Adjusting Delay Discounting.

Secondary Outcome Measures
NameTimeMethod
Self-controlUp to 12 weeks

Assessed with the Brief Self-Control Survey.

Latency to first relapseup to 12 weeks

Defined as the number of days until first relapse (any smoking for seven consecutive days). Will be assessed with the Timeline Follow-Back procedure administered by telephone. Analyzed using generalized mixed models.

7-day point prevalence abstinence ratesAt 4 and 12 weeks after quit date

Will be evaluated by cox proportional-hazards survival model analyses.

Number of days abstinentUp to 12 weeks

Will be evaluated by cox proportional-hazards survival model analyses.

Attentional, motor, and non-planning impulsivenessUp to 12 weeks

Assessed with the Barratt Impulsiveness Scale.

Behavioral inhibition and behavioral activationUp to 12 weeks

Assessed with the Behavioral Avoidance/Inhibition scales.

Ability to regulate behavior to achieve goalsUp to 12 weeks

Assessed with the Short Self-Regulation Questionnaire.

Trial Locations

Locations (1)

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

© Copyright 2025. All Rights Reserved by MedPath