Nicotine
- Generic Name
- Nicotine
- Brand Names
- Habitrol, Nicoderm C-Q, Nicorelief, Nicorette, Nicotrol
- Drug Type
- Small Molecule
- Chemical Formula
- C10H14N2
- CAS Number
- 54-11-5
- Unique Ingredient Identifier
- 6M3C89ZY6R
- Background
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
- Indication
For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
- Associated Conditions
- Withdrawal Nicotine
- Associated Therapies
- Smoking cessation therapy
Evaluating the Delivery and Effects of THC Vaping Liquids in the Bloodstream
- Conditions
- Interventions
- First Posted Date
- 2024-03-27
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- Roswell Park Cancer Institute
- Target Recruit Count
- 60
- Registration Number
- NCT06334016
- Locations
- 🇺🇸
Roswell Park Cancer Institute, Buffalo, New York, United States
Nicotine Virtual Reality Conditioned Place Preference
- Conditions
- Interventions
- First Posted Date
- 2024-02-14
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- University of Chicago
- Registration Number
- NCT06259630
- Locations
- 🇺🇸
University of Chicago Medical Center - Human Behavioral Pharmacology Lab, Chicago, Illinois, United States
Addictive Threshold of Nicotine
- First Posted Date
- 2023-10-24
- Last Posted Date
- 2024-03-06
- Lead Sponsor
- Yale University
- Target Recruit Count
- 36
- Registration Number
- NCT06096714
- Locations
- 🇺🇸
VA Healthcare System, West Haven, Connecticut, United States
Nicotine and Pavlovian Bias
- Conditions
- Interventions
- First Posted Date
- 2023-09-07
- Last Posted Date
- 2023-11-09
- Lead Sponsor
- University of Southern California
- Target Recruit Count
- 40
- Registration Number
- NCT06027723
- Locations
- 🇺🇸
University of Southern California, Los Angeles, California, United States
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
- Conditions
- Interventions
- First Posted Date
- 2023-08-21
- Last Posted Date
- 2023-08-21
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 48
- Registration Number
- NCT05999383
- Locations
- 🇺🇸
Zuckerberg San Francisco General Hospital, San Francisco, California, United States
Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine
- Conditions
- Interventions
- First Posted Date
- 2023-07-27
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 18
- Registration Number
- NCT05962229
- Locations
- 🇺🇸
Zuckerberg San Francisco General Hospital (ZSFG), San Francisco, California, United States
E-cigarette Nicotine Study
- Conditions
- Interventions
- First Posted Date
- 2021-01-14
- Last Posted Date
- 2022-08-26
- Lead Sponsor
- University of Vermont
- Target Recruit Count
- 77
- Registration Number
- NCT04709471
- Locations
- 🇺🇸
University of Vermont, Burlington, Vermont, United States
Do Flavors Increase the Addiction Potential of Nicotine?
- First Posted Date
- 2021-01-06
- Last Posted Date
- 2022-03-22
- Lead Sponsor
- University of Vermont
- Target Recruit Count
- 19
- Registration Number
- NCT04696380
- Locations
- 🇺🇸
University of Vermont, Burlington, Vermont, United States
Nicotine's Potential Abuse With Menthol
- First Posted Date
- 2020-09-01
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Yale University
- Target Recruit Count
- 16
- Registration Number
- NCT04535362
- Locations
- 🇺🇸
Department of Veterans Affairs Hospital, West Haven, Connecticut, United States
Effects of Menthol in E-cigarettes on Smoking Behaviors
- First Posted Date
- 2020-08-20
- Last Posted Date
- 2023-12-15
- Lead Sponsor
- Yale University
- Target Recruit Count
- 10
- Registration Number
- NCT04521647
- Locations
- 🇺🇸
Connecticut Mental Health Center, New Haven, Connecticut, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.