Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
VAMC, Denver, Colorado, United States
VA Greater Los Angeles Healthcare System, Los Angeles, California, United States
Veterans Affairs Medical Center, Durham, North Carolina, United States
VA Eastern Colorado Health Care System, Denver, Denver, Colorado, United States
University of Vermont, Burlington, Vermont, United States
Department of Internal Medicine, Mayo Foundation, Rochester, Minnesota, United States
Substance Abuse Treatment Center, VA Medical Center, West Haven, Connecticut, United States
General Internal Medicine, VA Medical Center, Minneapolis, Minnesota, United States
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, Texas, United States
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