Nicotine
- Generic Name
- Nicotine
- Brand Names
- Habitrol, Nicoderm C-Q, Nicorelief, Nicorette, Nicotrol
- Drug Type
- Small Molecule
- Chemical Formula
- C10H14N2
- CAS Number
- 54-11-5
- Unique Ingredient Identifier
- 6M3C89ZY6R
- Background
Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.
- Indication
For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
- Associated Conditions
- Withdrawal Nicotine
- Associated Therapies
- Smoking cessation therapy
Smoking Treatment and Exercise Program for Underserved Populations (STEP UP)
- First Posted Date
- 2016-08-19
- Last Posted Date
- 2018-07-13
- Lead Sponsor
- Duke University
- Target Recruit Count
- 11
- Registration Number
- NCT02873754
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Mobile Contingency Management for Marijuana and Tobacco Cessation
- First Posted Date
- 2016-08-17
- Last Posted Date
- 2020-02-07
- Lead Sponsor
- Duke University
- Target Recruit Count
- 7
- Registration Number
- NCT02869451
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)
- First Posted Date
- 2016-06-28
- Last Posted Date
- 2018-09-27
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 15
- Registration Number
- NCT02816138
- Locations
- 🇺🇸
Vanderbilt Psychiatric Hospital, Nashville, Tennessee, United States
RCT of an Internet Cessation Program Plus Online Social Network for HIV+ Smokers
- Conditions
- Interventions
- First Posted Date
- 2016-05-24
- Last Posted Date
- 2023-08-04
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 512
- Registration Number
- NCT02781090
- Locations
- 🇺🇸
Johns Hopkins, Baltimore, Maryland, United States
🇺🇸Montefiore Medical Center, Bronx, New York, United States
Control Systems Approach to Predicting Individualized Dynamics of Nicotine Cravings
- Conditions
- Interventions
- First Posted Date
- 2015-12-31
- Last Posted Date
- 2017-07-02
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 23
- Registration Number
- NCT02643914
- Locations
- 🇺🇸
Bioengineering Building , Stony Brook University, Stony Brook, New York, United States
Babies Living Safe and Smokefree
- Conditions
- Interventions
- First Posted Date
- 2015-11-11
- Last Posted Date
- 2022-03-15
- Lead Sponsor
- Temple University
- Target Recruit Count
- 396
- Registration Number
- NCT02602288
- Locations
- 🇺🇸
Temple University, Philadelphia, Pennsylvania, United States
🇺🇸N.O.R.T.H., Inc., Philadelphia, Pennsylvania, United States
The Use of Nicotine Patches Together With E-cigarettes (With and Without Nicotine) for Smoking Cessation
- Conditions
- Interventions
- First Posted Date
- 2015-08-13
- Last Posted Date
- 2021-08-19
- Lead Sponsor
- University of Auckland, New Zealand
- Target Recruit Count
- 1124
- Registration Number
- NCT02521662
- Locations
- 🇳🇿
National Institute for Health Innovation, University of Auckland, Auckland, North Island, New Zealand
Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette
- First Posted Date
- 2015-07-30
- Last Posted Date
- 2015-07-30
- Lead Sponsor
- Parc de Salut Mar
- Target Recruit Count
- 12
- Registration Number
- NCT02511704
- Locations
- 🇪🇸
Institut Hospital del Mar d'Investigacions Mèdiques-IMIM. Parc de Salut Mar., Barcelona, Spain
Effect of Nicotine on Brain Reward Pathways
- First Posted Date
- 2015-01-27
- Last Posted Date
- 2018-03-22
- Lead Sponsor
- Mclean Hospital
- Target Recruit Count
- 46
- Registration Number
- NCT02346539
- Locations
- 🇺🇸
McLean Hospital, Belmont, Massachusetts, United States
Effect of Smoking Reduction on Endothelial Glucocalyx and Vascular Function
- First Posted Date
- 2014-12-03
- Last Posted Date
- 2020-04-03
- Lead Sponsor
- University of Athens
- Target Recruit Count
- 600
- Registration Number
- NCT02307045
- Locations
- 🇬🇷
''Attikon'' University General Hospital, Athens, Attiki, Greece
Drug Development Updates
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