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The Effect of desmopressin administration on intraoperative blood loss of sinus surgery

Not Applicable
Recruiting
Conditions
Bleeding during endoscopic surgery of sinuses (FESS).
Chronic sinusitis
Registration Number
IRCT20101026005026N9
Lead Sponsor
Iran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
60
Inclusion Criteria

All patients must be 18–65 years old, who it is their first-time candidates for two-side FESS

Exclusion Criteria

Patients with a history of bleeding disorders or taking medications that may affect surgical homeostasis;
Poorly controlled hypertension or cerebrovascular disease;
A history of significant coronary artery disease or arrhythmia
Secondary surgery
Pregnancy
A compromised renal or hepatic function; and

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Intraoperative blood loss. Timepoint: Every 15 minuets from the begining of anesthesia until maximum 90 minutes. Method of measurement: Final intraoperative blood loss was confirmed at the end of each procedure by accounting for loss of blood and irrigation fluid into the suction canister, and nasopharyngeal packing (measured weight of packing on the electronic scale).;Quality of the surgical field during functional endoscopic sinus surgery. Timepoint: End of surgery. Method of measurement: A scoring scale adapted from Boezaart and van der merew.
Secondary Outcome Measures
NameTimeMethod
Bleeding after the surgery. Timepoint: Until 4 days after surgery. Method of measurement: Questionnaire.
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