Immediate necrosectomy vs. step-up approach after EUS-guided drainage of walled-off necrosis: a multicenter randomized controlled trial - WONDER-01 study

akai Yousuke0 个研究点目标入组 70 人开始时间: 2022年5月11日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•Patients with WON accoring to the revised Atlanta classification
•-The long axis of WON is 4 cm or larger
•-At least one of four conditions; signs of infection, Gastrointestinal symptoms, abdominal symptoms, obstructive jaundice
•-Patients who need drainage of WON
•-Age of 18 years or older
•-Patients or their representative provide informed consent
•-Patients who visited or are hospitalized to the participating institutions

•-WON inaccessible by EUS-guided approach
•-WON with an indwelling AXIOS
•-Severe coagulopathy; Platelet count <50,000/mm3 or PT-INR>1,5
•-Patients on antithrombotic agents which are unable to be stopped or modified according to the guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment
•-Patients who cannot tolerate endoscopic procedures safely
•-Pregnancy
•-Patients who are conidered as inappropriate for inclusion to the study

发起方

akai Yousuke