Effect of COVID-19 Infection on Obstertric Complications and Maternal Outcomes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- COVID-19
- Sponsor
- Tanta University
- Enrollment
- 260
- Locations
- 1
- Primary Endpoint
- Pregnancy related complications
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
This study aimed to evaluate the effect of COVID-19 infection on obstetric complications and maternal outcomes.
Detailed Description
During the SARS-CoV-2 pandemic, pregnant women were reported to have a higher susceptibility to COVID-19 infection. Pregnant women who tested positive for SARS-CoV-2 are at higher risk of a severe form of COVID-19, associated with higher rates of intensive care unit (ICU) admission and increased needs for respiratory support, compared to the age-matched non-pregnant population. Women infected during pregnancy also have an increased risk of adverse pregnancy outcomes including preterm-birth, with a significant proportion secondary to iatrogenic preterm birth due to maternal illness. Infection with SARS-CoV-2 during pregnancy has also been reported to be associated with a higher risk of stillbirth directly or indirectly caused by the virus. Infected pregnant patients tended to present asymptomatically with pre-Delta and Omicron variants, and symptomatically with Delta variant. A previous systematic review suggested that people who are pregnant did not have an increased risk of SARS-CoV-2 infection or symptomatic COVID-19, but they were at risk of severe COVID-19 compared with those who were not pregnant.
Investigators
Mai Nabil Ageez
Lecturer of Obstetrics and Gynecology, Faculty of Medicine, Tanta University, Tanta, Egypt.
Tanta University
Eligibility Criteria
Inclusion Criteria
- •Age from 18 to 40 years.
- •Pregnant women with COVID-19 infection diagnosed either by PCR or rapid test.
Exclusion Criteria
- •Patients vaccinated for COVID-19 before or during the current pregnancy.
Outcomes
Primary Outcomes
Pregnancy related complications
Time Frame: For one month
Pregnancy related complications as preterm birth, preeclampsia, intrauterine fetal demise (IUFD), increased cesarean section rate, postpartum hemorrhagic gastroenteritis (HGE) were collected
Secondary Outcomes
- Apgar score(For 5 minutes post-intervention)
- Intensive care unit admission rate(For one month)
- Use of mechanical ventilation(For one year)
- Incidence of death(For one month)