Clinical outcomes of patients with severe intestinal failure on intravenous nutrition at home.
- Conditions
- Home parenteral nutrition (HPN)Olive-oil-based Severe intestinal failureClinical outcomes
- Registration Number
- NL-OMON22519
- Lead Sponsor
- Radboudumc Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
HPN patients with olive-oil-based HPN for at least 3 months for at least 70% of the time.
- Patients >18 years.
Exclusion Criteria
HPN frequency <3 times per week.
Solely intravenous fluids depended patients.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Patient survival.
- Secondary Outcome Measures
Name Time Method 1. Relevant adverse events:<br /><br>- Early: hypersensitivity to lipid emulsion components<br /><br>- Delayed: bone disease.<br /><br>2. Serious adverse events (Life threatening events and Hospital admissions).<br /><br>3. Discontinuation of HPN and reason.<br /><br>4. Catheter-related bloodstream infections (incidende rate).<br /><br>5. Catheter-related occlusions (incidende rate).<br /><br>6. Need for intestinal transplantation (Incidence and cause).