Investigating the Role of Mucin and Mucin Glycosylating Enzymes in Nasopharyngeal Carcinoma and Salivary Gland Cancer and Their Correlation With Clinical Prognosis
- Conditions
- Nasopharyngeal CarcinomaSalivary Gland Cancer
- Registration Number
- NCT02401763
- Lead Sponsor
- National Taiwan University Hospital
- Brief Summary
Nasopharyngeal carcinoma (NPC) is the tenth leading cancers in Taiwan and investigating its biomarker is important for understanding the mechanism of its pathogenesis.
- Detailed Description
NPC is the tenth leading cancers in Taiwan and investigating its biomarker is important for understanding the mechanism of its pathogenesis.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 200
Inclusion Criteria
- NPC and salivary gland tumor diagnosed and treated in HTUH
Exclusion Criteria
- previous treatment or surgery
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The difference of expression level of mucin glycosylating enzymes (by immunohistochemistry) in nasopharyngeal carcinoma and salivary gland tissues 1~5 years after patients received definite therapy
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms of mucin glycosylation drive progression in NCT02401763 nasopharyngeal carcinoma and salivary gland cancer?
What role do mucin glycosylating enzymes play in NPC prognosis compared to standard biomarkers like EBV DNA?
Are mucin-related biomarkers in NCT02401763 predictive of treatment response in salivary gland cancer subtypes?
What adverse events are associated with mucin-targeted therapies in head and neck cancers beyond NCT02401763?
How do mucin expression patterns in NCT02401763 correlate with existing therapeutic strategies for NPC?