The hypercapnic ventilatory response measured with a rebreathing and steady-state apparatus in healthy subjects
Completed
- Conditions
- gezonde proefpersonenhealthynon-diseased
- Registration Number
- NL-OMON45318
- Lead Sponsor
- Medisch Spectrum Twente
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
between 18 and 65 years
written informed consent
Exclusion Criteria
history of cardiopulmonary disease, neuromuscular disease, kyphoscoliosis
drug abuse
use of respiratory stimulants or depressants
pregnancy
unable to understand english or dutch
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The main study endpoint is the reproducibility of the measurements. This is<br /><br>calculated by means of the ICC between the CO2 sensitivity slope of the first<br /><br>and second measurement per method. Thus the ICC of S1R1-S1R2 and S1SS1-S1SS2.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary endpoints are:<br /><br>-The experiences of the subjects with both measurements<br /><br>- Duration of the measurements<br /><br>- Costs of the method (sum of the costs of the various part of each method +<br /><br>costs of one long function analyst performing the measurement)</p><br>