ITMCTR2100004949Recruiting未知
Effect of synovial tissue nerve fiber production on pain and prognosis in knee osteoarthritis
Kunshan Third People's Hospital0 sitesStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional study
Eligibility Criteria
- Ages
- 40 to 80 (—)
- Sex
- All
Inclusion Criteria
- •1. Patients with symptomatic knee osteoarthritis, using the KOA diagnostic criteria in the 2007 edition of the Osteoarthritis Diagnostic and Treatment Guidelines;
- •2. Patients with painful knee osteoarthritis;
- •3. Subjects with pain score of at least 30 mm on 100 mm visual analogue scale;
- •4. Subjects over 40 years old;
- •5. Subjects who have not used easy layer application or Votalin ointment in the past;
- •6. Subjects who must sign the ICF before the start of the study.
Exclusion Criteria
- •1. The history of knee trauma or surgery within 6 months before this trial;
- •2. Arthroscopy or intra-articular injection therapy within 3 months before this trial;
- •3. Currently participating in other clinical trials;
- •4. Other concomitant knee diseases, such as rheumatoid arthritis(RA), gouty arthritis, etc.
- •5. Combination of mental disorders or other diseases that do not accurately describe the symptoms;
- •6. Combination of other serious diseases, such as severe diabetes,severe liver or kidney disease, malignancy, infectious diseases etc.;
- •7. History of severe skin allergies;
- •8. During pregnancy or lactation.
Investigators
Similar Trials
Not yet recruiting
Not Applicable
Association between synovial bioactive molecule profile and perioperative pain in patients receiving knee arthroplasty.Knee arthritisArthritisJPRN-jRCT1050210208Amaya Fumimasa100
Not yet recruiting
Not Applicable
Association between synovial bioactive molecule profile and chronic postoperative pain in patients receiving knee arthroplasty.Knee arthritisArthritisJPRN-jRCT1050210207Amaya Fumimasa120
Completed
Phase 4
Epidermal Nerve Fibre Density Reduction as a Function of Application Time of topical high-dose and low-dose CapsaiciHealthy volunteersDRKS00004587niversitätsklinik Wien12
Active, not recruiting
Not Applicable
Comparison of different Capsaicin doses and their effects on nerve fibres in the skiImpact of Capsaicin on epidermal nerve fibresEUCTR2012-002406-46-ATMedizinische Universität Wien, Universitätsklinik für Anästhesie, Allgemeine Intensivmedizin und Schmerztherapie
Active, not recruiting
Phase 1
The effect of saphenous nerve and obturator nerve block combined with intravenous given glucocorticoid compared with infiltration of local anesthetic in the tissue around the knee joint combined with intravenous given glucocorticoid, on opioid consumption and pain after total knee arthroplasty.The medical condition to be examined in this study is the first postoperative period after total knee replacement with a view to pain management.MedDRA version: 17.1Level: LLTClassification code 10038286Term: Regional nerve blockSystem Organ Class: 100000004865EUCTR2014-003343-35-DKThomas Fichtner Bendtsen