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Individualized anti-platelet therapy in patients with stable coronary artery disease undergoing stenting

Phase 1
Conditions
Chronic coronary syndrome, Stable coronary artery disease
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
CTIS2023-504078-39-01
Lead Sponsor
St Antonius Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
88
Inclusion Criteria

Patients of 18 years or older, Patients with Chronic Coronary Syndrome (CCS) undergoing successful elective percutaneous coronary intervention (PCI), Patients with written informed consent as approved by the ethics committee

Exclusion Criteria

•Contraindication to aspirin, •Suboptimal result of stenting as defined by the operator, preferably explained according the complex-PCI criteria, •Treatment with a strong CYP3A4 inhibitor or inducer, •Treatment with a strong CYP2C19 inhibitor or inducer, •Contraindication to ticagrelor, prasugrel or clopidogrel, •Planned cardiac valve surgery, •Need for chronic oral anticoagulation, •PCI when admitted for ACS, •Life expectancy < 1 year, •Unable or unwilling to provide informed consent, •Pregnancy, •History of definite stent thrombosis

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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