A Test of the Balance System in Vestibular Migraine

Not Applicable

• Conditions: Vestibular Migraine; Neurological - Other neurological disorders

• Registration Number: ACTRN12616000683437
• Lead Sponsor: Dr Rebecca KellyCampbell

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-25
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

For Vestibular Migraine group:

A.At least five episodes fulfilling criteria C and D
B.A current or past history of Migraine without aura or Migraine with aura
C.Vestibular symptoms of moderate or severe intensity, 3 lasting between 5 minutes and 72 hours
D.At least 50% of episodes are associated with at least one of the following three migrainous features:
1.headache with at least two of the following four characteristics:
a)unilateral location
b)pulsating quality
c)moderate or severe intensity
d)aggravation by routine physical activity
2.photophobia and phonophobia
3.visual aura
E.Not better accounted for by another ICHD-3 diagnosis or by another vestibular disorder.

The only criteria for the healthy controls are the exclusion criteria.

Exclusion Criteria

For Vestibular Migraine

1.conductive hearing loss, determined by either pure tone audiometry or tympanometry.
2.inability to maintain tonic EMG neck activity by raising their head from a supine position
3.inability to maintain eye gaze in the superomedial direction.

For Healthy Controls:

Exclusion criteria for healthy controls:
1.significant history of balance/vertigo problems, or headache/migraine.
2.conductive hearing loss, determined by either pure tone audiometry or tympanometry.
3.inability to maintain tonic EMG neck activity by raising their head from a supine position
4.inability to maintain eye gaze in the superomedial direction.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cVEMP interpeak amplitude<br>[All data is collected on one day for each participant.];cVEMP latency[All data is collected on one day for each participant.];cVEMP threshold[All data is collected on one day for each participant.]

Secondary Outcome Measures

Name	Time	Method
cVEMP prevalence (Primary)[All data is collected on one day for each participant.];oVEMP n10 amplitude (primary)[All data is collected on one day for each participant.];oVEMP latency (primary)[All data is collected on one day for each participant.];oVEMP threshold[All data is collected on one day for each participant.];oVEMP prevalence[All data is collected on one day for each participant.]