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Physical Activity Intervention for the Improvement of Pain in Young, Hispanic Breast Cancer Survivors

Not Applicable
Recruiting
Conditions
Breast Cancer
Interventions
Behavioral: Supportive Care (Fitbit)
Registration Number
NCT06260332
Lead Sponsor
New Mexico Cancer Care Alliance
Brief Summary

This clinical trial tests whether increased activity throughout the day can improve the chronic pain and associated symptoms that breast cancer survivors may experience after surgery. Staying active is a key factor of one's physical, mental, and social health and well-being. Moving more could also reduce pain and associated stress, anxiety, or depression. Using a fitness tracker may help patients to move around more, whether or not they choose to exercise. Information gathered from this study may help researchers learn how the use of a Fitbit tracker with health coaching may improve physical activity and reduce pain in young, Hispanic breast cancer survivors.

Detailed Description

PRIMARY OBJECTIVE:

I. To assess the feasibility of a physical activity intervention in young, Hispanic women with chronic post-operative pain after breast surgery for invasive breast cancer, termed post breast surgery pain syndrome (PBSPS) for this study.

SECONDARY OBJECTIVES:

I. To assess the preliminary efficacy of a physical activity intervention in decreasing pain in young, Hispanic women with PBSPS.

II. To assess the preliminary efficacy of the physical activity intervention in increasing physical activity and improving health-related quality of life (hrQOL).

OUTLINE:

Patients wear a Fitbit and use the Fitbit application to monitor their physical activity daily in weeks 2-12 with the goal of increasing their number of steps per day and their number of active hours per day. Starting at week 2, patients also receive educational materials and attend 6 calls over 20-60 minutes each with their health coach in weeks 2, 3, 5, 7, 9, and 11.

Recruitment & Eligibility

Status
RECRUITING
Sex
Female
Target Recruitment
25
Inclusion Criteria
  • Women who have completed surgery for invasive breast cancer >= 6 months prior to enrollment
  • Any breast surgery (lumpectomy or mastectomy)
  • Baseline low to moderate activity level (exercise less than 120 minutes a week)
  • PBSPS defined as pain in the area of breast surgery of at least moderate intensity (>= 4 on a scale of 1-10), located in the ipsilateral beast/chest wall, axilla or arm, lasting at least 6 months, and occurring at least 50% of the time
  • Self-identified as Hispanic/Latinx
  • Age, >= 18 and =< 60 years
  • Endocrine therapy and ovarian suppression is allowed
Exclusion Criteria
  • Metastatic or locally recurrent disease with no option for curative intent treatment
  • Meeting or exceeding physical activity guidelines (> 150 minutes per week of moderate-intensity exercise)
  • Unable to speak, read, and understand English or Spanish
  • Severe impairments (in seeing or hearing) or pre-existing medical limitations for engaging in daily physical activity. This is defined as the ability to walk 3 blocks without stopping to rest and without using an assistive device
  • Unwilling to use a study provided smartphone (if do not already own one) and wear activity trackers/monitors
  • Adults not able to consent are excluded from participation
  • Based on the age criteria (18 years and older), individuals who are not yet adults (infants, children, teenagers) may not participate in this study due to the same age criteria above
  • Pregnant women
  • Prisoners may not participate in this study as this is a study of free-living individuals

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Supportive Care (Fitbit)Supportive Care (Fitbit)Patients wear a Fitbit and use the Fitbit application to monitor their physical activity daily in weeks 2-12 with the goal of increasing their number of steps per day and their number of active hours per day. Starting at week 2, patients also receive educational materials and attend 6 calls over 20-60 minutes each with their health coach in weeks 2, 3, 5, 7, 9, and 11.
Primary Outcome Measures
NameTimeMethod
Recruitment rate (Feasibility)Up to 1 year

This study will be considered feasible with the recruitment of 25 breast cancer patients.

Adherence rate (Feasibility)Up to 12 weeks

This study will be considered feasible if participants complete at least 4 of 5 health coaching sessions (80%).

Retention rate (Feasibility)Up to 12 weeks

This study will be considered feasible if 80% of patients complete all pre and post assessments.

Incidence of adverse eventsUp to 12 weeks

Safety will be tracked by the study team.

Secondary Outcome Measures
NameTimeMethod
Change in chronic post-surgical painAt 13 weeks

Reducing chronic post-surgical pain will be measured using the Defense and Veterans Pain Rating Scale. Will also be assessed by Bodily Threat Monitoring Scale and pain self-efficacy questionnaire. Will summarize change scores with means and standard deviations, or medians and interquartile ranges, and obtain 95% confidence intervals. Will perform one-sided paired t-tests, or Wilcoxon signed rank tests.

Change in physical activityAt 13 weeks

Increasing physical activity will be measured using accelerometry data using the activePAL activity monitor. Will summarize change scores with means and standard deviations, or medians and interquartile ranges, and obtain 95% confidence intervals. Will perform one-sided paired t-tests, or Wilcoxon signed rank tests.

Change in health-related quality of life (hrQOL)At 13 weeks

Improvement in hrQOL will be measured using Patient-Reported Outcomes Measurement Information System surveys. Will summarize change scores with means and standard deviations, or medians and interquartile ranges, and obtain 95% confidence intervals. Will perform one-sided paired t-tests, or Wilcoxon signed rank tests.

Trial Locations

Locations (1)

University of New Mexico Comprehensive Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

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