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The effect of rhubarb (Rheum ribes L.) syrup in Children with acute diarrhea

Phase 3
Recruiting
Conditions
Acute diarrhea.
Viral and other specified intestinal infections
Registration Number
IRCT20200105046009N5
Lead Sponsor
Babol University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
96
Inclusion Criteria

Children 1 to 6 years
Acute diarrhea (loose stools for more than 3 times a day) in the last 72 hours
Stool white blood cell count less than 5 / HPF in stool with or without mucus or blood
Dehydration mild to moderate

Exclusion Criteria

More than three days have passed since the onset of diarrhea
Children treated with antibiotics or antidiarrheal drugs in the last 3 days
History of pneumonia, sepsis, meningitis, or toxic colitis during diarrhea
Entamoeba histolytica cyst, Giardia lamblia trophozoite in stool exam
Dysentery (infectious or non-infectious )
Dry milk consumption
Severe malnutrition (weight less than 60% or weight/height less than 70%)
History of known chronic diseases
Any type of food allergy
Use of probiotics
Immunodeficiency
Other infections including urinary tract infections

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Time to recovery. Timepoint: Counting the days of diarrhea up to the normal defecation. Method of measurement: Recovery time from acute diarrhea is defined as the time interval between admission and cessation of diarrhea or the first normal bowel movements, which in the Bristol stool diagram is equivalent to a score below 5.
Secondary Outcome Measures
NameTimeMethod
Duration of hospitalization. Timepoint: Counting the day of hospitalization (the days from hospitalization up to the discharge). Method of measurement: Counting the hospitalization days.
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