Clinical efficacy and safety observation of Bushen Zhuangjin Decoction in the treatment of early and middlestage knee osteoarthritis
- Conditions
- knee osteoarthritis
- Registration Number
- ITMCTR2024000094
- Lead Sponsor
- Henan University of Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
1) Patients who meet the diagnostic criteria for KOA (unilateral or bilateral);
2) Patients aged between 50 and 70 years old, both male and female;
3) The X-ray K-L grade of the knee joint belongs to grade II-III;
4) KOA stage belongs to the early and middle stages;
5) Patients with good basic conditions, suitable for drug treatment, and no obvious indications of surgery;
6) The patient had good compliance and signed the informed consent.
1) Have taken traditional Chinese medicine decoction, proprietary Chinese medicine or other Western medicine with KOA treatment in the past week;
2) Participants in other research projects before enrollment;
3) Patients with knee joint tumor, tuberculosis, rheumatism, rheumatoid arthritis, gouty arthritis and other diseases;
4) Patients who have undergone knee replacement;
5) Pregnant or planning to become pregnant or lactating women;
6) Patients with severe primary diseases of the heart, cerebrovascular and hematopoietic systems, mental diseases, malignant tumors, and liver and kidney dysfunction;
7) Participants in other clinical trials that affect the evaluation of the results of this study.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method