Assessing the Impact of COVID-19 on HMPV Incidence and Severity Among Adults

Completed

• Conditions: The Prevalance of HMPV After COVID-19 Pandemic; The Importance of Accurate Diagnosis for HPMV
• Interventions: Other: Observation

• Registration Number: NCT06309212
• Lead Sponsor: Acibadem University

Brief Summary

Human metapneumovirus (HMPV) is primarily recognized as a childhood pathogen, but its impact on adults remains largely underestimated. This study investigates the prevalence, clinical characteristics, and post-COVID-19 trends of HMPV infection among adults in Istanbul, Turkey.

Detailed Description

Human metapneumovirus (HMPV) is primarily recognized as a childhood pathogen, but its impact on adults remains largely underestimated. This study investigates the prevalence, clinical characteristics, and post-COVID-19 trends of HMPV infection among adults in Istanbul, Turkey.

Study Timeline

• Study Start: 2023-12-15
• Primary Completion: 2023-12-30
• Study Completion: 2024-01-30
• Status Verified: 2024-03
• Study First Submitted: 2024-03-12
• Study First Submitted QC: 2024-03-12
• Last Update Submitted: 2024-03-12
• Study First Posted: 2024-03-13
• Last Update Posted: 2024-03-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2197

Inclusion Criteria

• Adults >18 years
• Patients with acute respiratory tract infection symptoms
• Patients who underwent multiplex PCR testing for respiratory viruses

Exclusion Criteria

• Patients for whom no respiratory viral panel test was conducted

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Pre-COVID period	Observation	January 2016 to January 2020
Post-COVID period	Observation	January 2021 to September 2023

Primary Outcome Measures

Name	Time	Method
Prevalence of HMPV infection in adults pre- and post-COVID-19 pandemic	Between 2016-2020 (pre-COVID) and 2021-2023 (post-COVID)	Analyse of data from adults with respiratory tract infections who were tested for various respiratory viruses using a multiplex PCR assay

Secondary Outcome Measures

Name	Time	Method
Comparison of HMPV with other respiratory viruses in adults	Between 2016-2020 (pre-COVID) and 2021-2023 (post-COVID)	Analyse of data from adults with respiratory tract infections who were tested for various respiratory viruses using a multiplex PCR assay

Trial Locations

Locations (1)

Acibadem University; 🇹🇷 Istanbul, Turkey