Analysis of the Voice in Patients with Essential Tremor (ET) and Deep Brain Stimulation (DBS): an electroglottography study

• Conditions: Stimulation induced dysarthria; G25.0; Essential tremor

• Registration Number: DRKS00012379
• Lead Sponsor: niversitätsklinikum Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-07-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting stopped after recruiting started
• Sex: All
• Target Recruitment: 11

Inclusion Criteria

Patients, male or female, with Essential Tremor and DBS in the Ventral intermediate nucleus thalami (VIM)
Patients have to be between 18 and 80 years of age
Patients have to be german native speakers
Patients must be capable to give their informed consent and must agree to the study

Exclusion Criteria

Disease that could influence the voice besides Essential Tremor
Patients were implanted with DBS-device during the last three months

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effect of Deep Brain Stimulation of the nucleus ventralis intermedius on motor control of the lanynx in patients with essential tremor. We measure and analyse vocal fold vibrations by means of Electroglottography in both stimulation-ON and stimulation-OFF conditions.

Secondary Outcome Measures

Name	Time	Method
The effect of Deep Brain Stimulation of the nucleus ventralis intermedius on tremor in patients with essential tremor. We measure and analyse tremor by means of the Tremor Rating Scale in both stimulation-ON and stimulation-OFF conditions.