MedPath

Home Hospital for Suddenly Ill Adults

Not Applicable
Conditions
Asthma
Chronic Kidney Diseases
Heart Failure
Infection
Anticoagulants; Increased
COPD
Gout Flare
Hypertensive Urgency
Atrial Fibrillation Rapid
Interventions
Other: Home Hospitalization
Registration Number
NCT03524222
Lead Sponsor
Brigham and Women's Hospital
Brief Summary

The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be delivered in the home with equal quality and safety, reduced cost, and improved patient experience.

Detailed Description

Hospitals are the standard of care for acute illness in the United States, but hospital care is expensive and often unsafe, especially for older individuals. While admitted, 20% suffer delirium, over 5% contract hospital-acquired infections, and most lose functional status that is never regained. Timely access to inpatient care is poor: many hospital wards are typically over 100% capacity, and emergency department waits can be protracted. Moreover, hospital care is increasingly costly: many internal medicine admissions have a negative margin (i.e., expenditures exceed hospital revenues) and incur patient debt.

The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be delivered in the home with equal quality and safety, 20% reduced cost, and 20% improved patient experience. While this is the standard of care in several developed countries, only 2 non-randomized demonstration projects have been conducted in the United States, each with highly local needs. Taken together, home hospital evidence is promising but falls short due to non-robust experimental design, failure to implement modern medical technology, and poor enlistment of community support.

The home hospital module offers most of the same medical components that are standard of care in an acute care hospital. The typical staff (medical doctor \[MD\], registered nurse \[RN\], case manager), diagnostics (blood tests, vital signs, telemetry, x-ray, and ultrasound), intravenous therapy, and oxygen/nebulizer therapy will all be available for home hospital. Optional deployment of food services, home health aide, physical therapist, occupational therapist, and social worker will be tailored to patient need. Home hospital improves upon the components of a typical ward's standard of care in several ways:

Point of care blood diagnostics (results at the bedside in \<5 minutes); Minimally invasive continuous vital signs, telemetry, activity tracking, and sleep tracking; On-demand 24/7 clinician video visits; 4 to 1 patient to MD ratio, compared to typical 16 to 1; Ambulatory/portable infusion pumps that can be worn on the hip; Optional access to a personal home health aide Should a matter be emergent (that is, requiring in-person assistance in less than 20 minutes), then 9-1-1 will be called and the patient will be returned to the hospital immediately. In previous iterations of home hospital this happens in about 2% of patients.

Clinical parameters measured will be at the discretion of the physician and nurse, who treat the participant following evidence-based practice guidelines, just as in the usual care setting. In addition, the investigators will be tracking a wide variety of measures of quality and safety, including some measures tailored to each primary diagnosis.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
3000
Inclusion Criteria
  • Resides within either a 5-mile or 20 minute driving radius of emergency department
  • Has capacity to consent to study OR can assent to study and has proxy who can consent
  • >= 18 years-old
  • Can identify a potential caregiver who agrees to stay with patient for first 24 hours of admission. Caregiver must be competent to call care team if a problem is evident to her/him. After 24 hours, this caregiver should be available for as-needed spot checks on the patient. This criterion may be waived for highly competent patients at the patient and clinician's discretion.
  • Primary or possible diagnosis of cellulitis, heart failure, complicated urinary tract infection, pneumonia, COPD/asthma, other infection, chronic kidney disease, malignant pain, diabetes and its complications, gout flare, hypertensive urgency, previously diagnosed atrial fibrillation with rapid ventricular response, anticoagulation needs, or a patient who desires only medical management that requires inpatient admission, as determined by the emergency room team.
Exclusion Criteria
  • Undomiciled
  • No working heat (October-April), no working air conditioning if forecast > 80°F (June-September), or no running water
  • On methadone requiring daily pickup of medication
  • In police custody
  • Resides in facility that provides on-site medical care (e.g., skilled nursing facility)
  • Domestic violence screen positive
  • Acute delirium, as determined by the Confusion Assessment Method
  • Cannot establish peripheral access in emergency department (or access requires ultrasound guidance)
  • Secondary condition: end-stage renal disease, acute myocardial infarction, acute cerebral vascular accident, acute hemorrhage
  • Primary diagnosis requires multiple or routine administrations of intravenous narcotics for pain control
  • Cannot independently ambulate to bedside commode
  • As deemed by on-call medical doctor, patient likely to require any of the following procedures: computed tomography, magnetic resonance imaging, endoscopic procedure, blood transfusion, cardiac stress test, or surgery
  • High risk for clinical deterioration
  • Home hospital census is full (maximum 5 patients at any time)

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Home HospitalizationHome HospitalizationPatients will return home after triage, diagnosis, and the beginning of treatment in the emergency department with a set of specialized patient-tailored services (listed above). On discharge and 30 days after discharge, they will be interviewed regarding their hospitalization and health.
Primary Outcome Measures
NameTimeMethod
Total direct cost of hospitalization, $From date of admission to date of discharge, an expected average of 4 days
Secondary Outcome Measures
NameTimeMethod
Direct margin, $From date of admission to date of discharge, an expected average of 4 days

Direct margin from total cost of hospitalization

Length of stay, daysFrom date of admission to date of discharge, an expected average of 4 days
All-cause readmission(s) after index, y/nDay of discharge to 30 days later
Emergency Department observation stay(s) after index hospitalization, y/nDay of discharge to 30 days later
Emergency Department visit(s) after index hospitalization, y/nDay of discharge to 30 days later
Hours of sleep per day, #From date of admission to date of discharge, an expected average of 4 days
Hours of activity per day, #From date of admission to date of discharge, an expected average of 4 days
3-item Care Transition Measure, score30 days after discharge
Imaging, #From date of admission to date of discharge, an expected average of 4 days

Count of any diagnostic imaging (for example, x-ray, computed tomography, magnetic resonance, ultrasound, and nuclear imaging) that occurred through the course of the hospitalization.

Lab orders, #From date of admission to date of discharge, an expected average of 4 days

Count of any lab order (for example, basic metabolic panel, complete blood count, hepatic function panel) that occurred through the course of the hospitalization.

Unplanned readmission(s) after index, y/nDay of discharge to 30 days later
Delirium, y/nFrom date of admission to date of discharge, an expected average of 4 days
Transfer back to hospital, y/nFrom date of admission to date of discharge, an expected average of 4 days
Steps per day, #From date of admission to date of discharge, an expected average of 4 days
Short Form 130 days prior to admission (asked on day of admission), at admission, at discharge (the day the patient leaves the hospital environment), and at 30 days after discharge

1-5 Likert scale: Excellent, very good, good, fair poor

Picker Experience Questionnaire, score30 days after discharge
Global satisfaction with care, score30 days after discharge
Unplanned readmission(s) after index, #Day of discharge to 30 days later
Emergency Department observation stay(s) after index hospitalization, #Day of discharge to 30 days later
Total cost, 30-day post dischargeDay of admission to 30-days post-discharge
Emergency Department visit(s) after index hospitalization, #Day of discharge to 30 days later
Direct margin, modeled with backfillFrom date of admission to date of discharge, an expected average of 4 days

Backfill uses a model that estimates the cost of patients who take the place of home hospital patients

All-cause readmission(s) after index, #Day of discharge to 30 days later
Hours of sitting upright per day, #From date of admission to date of discharge, an expected average of 4 days
EuroQol-5D-5L, composite scoreAt admission, at discharge (the day the patient leaves the hospital environment), and at 30 days after discharge
Activities of daily living, score30 days prior to admission (asked on day of admission), at admission, at discharge (the day the patient leaves the hospital environment), and at 30 days after discharge
Instrumental activities of daily living, score30 days prior to admission (asked on day of admission), at admission, at discharge (the day the patient leaves the hospital environment), and at 30 days after discharge
Qualitative interview30 days after discharge

Trial Locations

Locations (2)

Brigham and Women's Hospital

🇺🇸

Boston, Massachusetts, United States

Brigham and Women's Faulkner Hospital

🇺🇸

Boston, Massachusetts, United States

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