Comparison of 2 steroid tapering protocol in adult minimal change disease.
Phase 4
- Conditions
- Health Condition 1: null- Adult minimal change disease
- Registration Number
- CTRI/2015/12/006439
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 188
Inclusion Criteria
1. Nephrotic syndrome
2. Biopsy proved minimal change disease
Exclusion Criteria
1. Hepatitis B, C or human immunodeficiency virus-I/II infection
2. Prior use of steroids/ immunosuppressive medication for any indication.
3. Persistent renal dysfunction even after remission of proteinuria
4. Nephrotic syndrome requiring >8 weeks to achieve remission
5. History of Diabetes mellitus (DM)
6. Abnormal liver function tests
7. Presence of active sediments in the urine defined as > 5 RBCs/ HPF in unspun urine
8. Anti nuclear antibody positivity
9. Drug induced MCD (Analgesic or omeprazole induced)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method