Comparing the effect of propofol and sevoflurane as anaesthetic agent on cerebral oxygenation using SjVO2 as parameter and effect on levels of IL-6 in patient undergoing surgery for traumatic brain injury.
Phase 1
Completed
- Conditions
- Health Condition 1: G00-G99- Diseases of the nervous systemHealth Condition 2: null- Head Injury patients
- Registration Number
- CTRI/2018/02/012139
- Lead Sponsor
- PGIMER Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 42
Inclusion Criteria
1. Patients with Isolated brain injury
2. Patients who had operable Acute Subdural Hematoma (SDH), brain
contusion or both
3. ASA IE-IIE patients
Exclusion Criteria
(1) Patients with motor response < 3 in Glasgow coma score (GCS) scale.
(2) Patients in shock (SBP <90 mm of Hg) even after resuscitation and before
induction of anaesthesia.
(3) Any comorbidity other than hypertension or diabetes (i.e. Coronary artery
disease, COPD, Hepatic or Renal impairment).
(4) Patients who had polytrauma.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method