DOC Utility: Simple Screening of Depression, Obstructive Sleep Apnea and Cognitive Impairment to Identify Stroke Clinic Patients at Risk of Adverse Outcomes
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 6,500
- 试验地点
- 1
- 主要终点
- Number of Participants with any Adverse Event
研究概览
简要总结
The primary objective of this study is to determine whether baseline DOC screening can add to clinical and demographic data to predict the occurrence of a composite negative outcome (any of: recurrent stroke, myocardial infarction, death, or admission to a long-term care (LTC) / complex continuing care (CCC) facility) within one year of screening, in stroke prevention clinic patients.
详细描述
The DOC screen will be routinely applied to all patients presenting to three high volume Regional Stroke Prevention Clinics (combined first visits >2,800 patients per year). Data will be abstracted from the patient chart using methodologies developed and validated in the Registry of the Ontario Stroke Network. The investigators have REB approval to collect this data and to link with administrative datasets through the Institute for Clinical and Evaluative Sciences (ICES). The investigators will use regression models to determine whether DOC screen scores add to baseline clinical and demographic data to predict the main negative outcomes. The investigators hope to identify which patients presenting to TIA/stroke prevention clinics are at highest risk of adverse long-term events so focused interventions can be developed to improve survival, outcomes and function of stroke prevention clinic patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Consecutive patients referred to regional stroke prevention clinics.
- •This includes those discharged from hospital with a diagnosis of stroke or TIA, as well as emergency department referrals.
- •The DOC CRF will also be completed for patients who are unable to complete the screen due to severe aphasia, severe motor dysfunction and language barriers (those who are not fluent in English without translation available).
排除标准
- •Patients whose reason for referral to the clinic is neither Stroke nor TIA, as well as those who have been admitted to LTC/CCC facilities at the time of clinic visit.
结局指标
主要结局
Number of Participants with any Adverse Event
时间窗: 1 Year from Initial Screen Date
A composite negative outcome will be created, defined as the occurrence of any recurrent stroke, myocardial infarction, death, or admission to a long-term care (LTC) / complex continuing care (CCC) facility within one year of screening.
次要结局
- Number of Participants with recurrent stroke(1 Year from Initial Screen Date)
- Incidence of DOC co-morbidities(1 Year from Initial Screen Date)
- Number of Participants with myocardial infarction(1 Year from Initial Screen Date)
- Number of Participants who died(1 Year from Initial Screen Date)
- Number of Participants who have been admitted to a long-term care or complex continuing care facility(1 Year from Initial Screen Date)
研究者
Dr. Richard H. Swartz
Principle Investigator
Sunnybrook Health Sciences Centre