Energy Expenditure and Body Composition of Infants and Young Children (6-24 Months Old) in Asia
- Conditions
- Energy ExpenditureInfant and Young Child FeedingBody CompositionInfants and Young Children
- Interventions
- Other: No intervention
- Registration Number
- NCT06287697
- Lead Sponsor
- Mahidol University
- Brief Summary
This project is a collaboration between International Atomic Energy Agency (IAEA), FAO Regional Office for Asia and The Pacific, and Mahidol University, Thailand to carry out the study on doubly-labeled water for assessment of total energy expenditure and body composition among infants and young children aged 6-23 months old. Thailand conducted a longitudinal study with participation from 4 other countries, namely, Pakistan, Philippines, Sri Lanka and Vietnam, in undertaking the same assessments in a cross-sectional design.
- Detailed Description
The current international recommendations on energy requirements for children aged 6-24 months were established based on data from the Western populations. More human data of healthy children from the developing countries where the living conditions may not be as favourable for child growth and development would be needed to ascertain the validity of the global recommendation. The role of the doubly-labelled water (DLW) technique in measuring total daily energy expenditure to derive energy requirements for humans was also highlighted. Low and middle income countries in Asian countries have undergone the nutrition transition and malnutrition on both ends of the spectrum emerge as significant nutrition challenges during this critical period of growth. Unfortunately, data on body composition, i.e., the relative amounts of fat and lean or fat-free tissue which constitutes quality normal growth beyond anthropometric measurements are scarce. These data will also be needed to guide the infant and young child feeding (IYCF) recommendations for good nutrition and health and to prevent all forms of malnutrition in the region.
This project addressed the need to fill the information gap for the region, and potentially be included for making revision on energy requirement recommendations for infants and young children (IYC) for Asia and beyond. Building on the previous technical cooperation between institutions in Southeast and South Asia with the International Atomic Energy Agency (IAEA) on stable isotopic techniques for health and nutrition well-being, this project is a collaboration between IAEA, FAO Regional Office for Asia and The Pacific, and Mahidol University, Thailand to carry out the study on doubly-labeled water for assessment of total energy expenditure and body composition among infants and young children aged 6-23 months old. Thailand conducted a longitudinal study with participation from 4 other countries, namely, Pakistan, Philippines, Sri Lanka and Vietnam, in undertaking the same assessments in a cross-sectional design.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 391
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Cross-sectional study-Pakistan No intervention Children aged 6-8, 9-11, 12-14, 15-17, 18-20, 21-23 months, both sexes. Longitudinal study-Thailand No intervention Cohort 1: 60 children were started at 6-8 months old, and were followed-up at 9-11, 12-14 and 15-17 months old. Cohort 2: 71 children were started at 12-14 months old, were followed-up 15-17, 18-21 and 21-24 months old. Cross-sectional study-Philippines No intervention Children aged 6-8, 9-11, 12-14, 15-17, 18-20, 21-23 months, both sexes. Cross-sectional study-Vietnam No intervention Children aged 6-8, 9-11, 12-14, 15-17, 18-20, 21-23 months, both sexes. Cross-sectional study-Sri Lanka No intervention Children aged 6-8, 9-11, 12-14, 15-17, 18-20, 21-23 months, both sexes.
- Primary Outcome Measures
Name Time Method Body composition assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Body composition assessed using doubly labelled water (DLW) technique
Total Energy Expenditure assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Total Energy Expenditure assessed using doubly labelled water (DLW) technique
- Secondary Outcome Measures
Name Time Method Head circumference assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Head circumference of infants in centimeters
Dietary intake assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months 24-hr recall was administered for 3 days to obtain nutrient intakes from breast milk and diet
Weight assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Body weight of infants in kilograms
Subscapular skinfold thickness assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Subscapular skinfold thickness of the left side in millimeters
Length assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Lenght of infants in centimeters
Mid-upper arm circumference assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Mid-upper arm circumference of the left arm in centimeters
Triceps skinfold thickness assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months Triceps skinfold thickness of the left arm in millimeters
Infant and Young Child Feeding (IYCF) assessed at aged 6-8, 9-11, 12-14, 15-17, 18-20, and 21-23 months IYCF indicators were determined using the IYCF questionnaire IYCF practices were assessed using the IYCF , breast milk intake, dietary intake
Trial Locations
- Locations (1)
Institute of Nutrition, Mahidol University
🇹ðŸ‡Salaya, Nakhon Pathom, Thailand