Evaluation of Energy Expenditure, Body Composition and Recovery Rates in Children With Severe Acute Malnutrition

Not Applicable

Completed

• Conditions: Children; Malnutrition
• Interventions: Behavioral: Nutrition education; Dietary Supplement: RUTF

• Registration Number: NCT01144806
• Lead Sponsor: Aga Khan University

Brief Summary

This project is being conducted with an aim to find out energy expenditure, body composition and recovery rates in children with severe acute malnutrition (SAM) receiving community-based nutritional rehabilitation therapy

Detailed Description

Objectives

1. To assess energy expenditure and body composition by stable isotope techniques in children with Severe Acute Malnutrition

2. To evaluate the potential usefulness of body composition assessment as a predictor of outcome in children with SAM, based on stable isotope technique and multi-frequency bioelectrical impedance analysis (BIA)

Inclusion criteria

* Parents of children of age 6 months to 3 years

* Resident of study area

Exclusion criteria

* Children with congenital malformations

* Chronic debilitating illnesses

* Refusal by parents to enroll in study

Study Timeline

• Study Start: 2010-06
• Study First Submitted: 2010-06-15
• Study First Submitted QC: 2010-06-15
• Study First Posted: 2010-06-16
• Primary Completion: 2011-08
• Study Completion: 2011-08
• Status Verified: 2012-02
• Last Update Submitted: 2012-02-23
• Last Update Posted: 2012-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Parents of children of age 6 months to 3 years
• Resident of study area

Exclusion Criteria

• Children with congenital malformations
• Chronic debilitating illnesses
• Refusal by parents to enroll in study

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Group 1	Nutrition education	Parent/care givers of children with severe malnutrition in enrolled in this group will be given nutrition education using the principles of infant and young child feeding (IYCF) and dietary diversification
Group 2	RUTF	Ready to use therapeutic food (RUTF / PlumpyNut)will be provided to parent/care givers of children with severe malnutrition in enrolled in this group

Primary Outcome Measures

Name	Time	Method
Body composition	12 weeks

Trial Locations

Locations (2)

Aga Khan University; 🇵🇰 Karachi, Sindh, Pakistan

Aga Khan Univeristy; 🇵🇰 Karachi, Sindh, Pakistan