Effect, mechanism and macro-micro-metastatic standard for the precise treatment of small vascular disease of lower extremity

Phase 1

• Conditions: Small vessel disease of lower extremities

• Registration Number: ITMCTR2000003648
• Lead Sponsor: Fudan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: Male
• Target Recruitment: Not specified

Inclusion Criteria

1. Meet the lower extremity small vascular disease early Western medicine diagnosis standard.
2. Meet the heat depression poison gathering Pulse stagnation syndrome of traditional Chinese medicine diagnostic standards;
3. Aged 30 to 75 years old;
4. Understand, agree to participate in this study and sign an informed consent.

Exclusion Criteria

1. Complicated with severe heart, liver, kidney, blood system and other diseases, or other serious primary diseases, mental illness;
2. Allergy to drugs in treatment programmes;
3. Pregnant or lactating women;
4. According to the researcher's' s judgement, there are other circumstances which reduce the likelihood or complicate it;
5. Participated in or is participating in other clinical researchers 1 month before joining the group;
6. Patients who had taken or were taking other medications for lower extremity small vascular disease the month before entering the group.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
TCM Syndrome Integr;CTA of lower extremity artery;Symptoms;DSA of lower extremity artery;Signs;

Secondary Outcome Measures

Name	Time	Method
Angiitis-associated antibodies;Blood flow;Microinflammation indicators;Sugar metabolism;Urine Biochemistry;Fat Metabolism;