DRKS00030741
Not yet recruiting
Not Applicable
Behavioral & neurocognitive bases of social interaction - BENESOCIA
Institut für klinische Neurowissenschaften und medizinische Psychologie, Heinrich-Heine-Universität Düsseldorf0 sites300 target enrollmentFebruary 17, 2023
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Autism spectrum disorder
- Sponsor
- Institut für klinische Neurowissenschaften und medizinische Psychologie, Heinrich-Heine-Universität Düsseldorf
- Enrollment
- 300
- Status
- Not yet recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •4 groups of patients / participants which fulfill following criteria:
- •\- Healthy controls (n \= 60\)
- •\- ASD patients as diagnosed based on ADOS\-2/ADI\-R and a clinical assessment by a qualified psychiatrist (n \= 60\).
- •\- SCZ patients as diagnosed based on a clinical assessment by a qualified psychiatrist (n \= 60\)
- •\- SAD patients as diagnosed on a clinical assessment by a qualified psychiatrist (n \= 60\).
- •\- OCD patients as diagnosed on a clinical assessment by a qualified psychiatrist (n \= 60\).
- •\- Ability to understand the study procedure
- •\- Informed consent: A declaration of informed consent has to be signed and personally dated by the subject.
Exclusion Criteria
- •\- Presence of disorders other than ASD, SCZ, SAD and OCD, which may deteriorate social functioning, motor function or cognitive abilities such as dementia, severe arthritis, drug/alcohol abuse, Alzheimer’s Disease, or stroke. However, because of high co\-occurrence rate of conditions such as depressive disorders in ASD, SCZ, SAD and OCD, such disorders will be controlled for in the analyses but will not constitute a hard exclusion criterion. We will, however, attempt to recruit mainly individuals with no comorbidities.
- •\- Inability to remain motionless in the fMRI scanner without involuntary movements providing intolerable artifacts
- •\- Inability to give informed consent
- •\- Claustrophobia
- •\- Pregnancy
- •\- MRI incompatible implants, such as cardiac pacemakers or magnetic objects
- •\- Permanent makeup
- •\- Large tattoos particularly in or near the imaging area
- •Abandon criteria:
- •\- Occurrence of any exclusion criterion either at the time of recruitment or revealed after/during measurement such as incidental findings in the MRI images
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
eural basis of cognitive responses toward social stressorsHealthy individualsJPRN-UMIN000035206ational Institutes for Quantum Science and Technology Quantum Life and Medical Science Directorate Institute for Quantum Medical Science36
Completed
Not Applicable
The neural substrate of cognitive and social-emotional apathy in patients with schizophreniaapathylistlessness10039628NL-OMON43784niversitair Medisch Centrum Groningen80
Not yet recruiting
Not Applicable
Effects of Social Cognition and Interaction Training (SCIT) on EmploymentSchizophreniaJPRN-jRCT1020210045Tsunaiguchi Hiroki50
Completed
Not Applicable
Cerebral control of social behaviour in social anxiety disordersocial anxiety disorderSocial phobia10002861NL-OMON33987Radboud Universiteit Nijmegen48
Not yet recruiting
Not Applicable
Adaptation and feasibility of Social Cognition and Interaction Training (SCIT) for persons with SchizophreniaCTRI/2022/04/042305IMHANS