Phenomic studies on heart failure-related TCM Zhenghou

Phase 1

• Conditions: Heart failure

• Registration Number: ITMCTR2000002932
• Lead Sponsor: Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion criteria for patients:
(1) Diagnostic standards of Western medicine: refer to Chinese guidelines for the diagnosis and treatment of heart failure 2018;
(2) Traditional Chinese medicine(TCM)diagnostic criteria: refer to the scoring criteria for the phenotype group of xin qi deficiency designed by this research group (see the attached table), and 3 attending physicians and above have made the dialectical classification, which conforms to the dialectical scoring criteria for xin qi deficiency designed by researchers;
(3) Aged >=18 years;
(4) Those who voluntarily participate in the experimental study and have signed the informed consent.
Inclusion criteria for healthy people:
(1) No internal medical diseases such as coronary heart disease, hypertension, kidney disease, tumor; physical examination, laboratory examination, electrocardiogram examination have no obvious abnormalities (relevant examination reports can be provided for the past three months);
(2) Male or female aged >=18 years;
(3) There are no bad habits such as smoking, alcoholism, and drug use, and the rules of daily life;
(4) No intestinal infection in one month;
(5) Not using antibiotics and probiotics, and drinking yogurt within one month;
(6) Do not use any antibiotic drugs during voluntary research;
(7) Did not participate in a clinical trial within 3 months before the trial;
(8) Tolerated venipuncture, no history of halo acupuncture; sampling process meets the requirements of the hospital ethics committee;
(9) The subject is informed and agrees to cooperate;
(10)Dialectical by traditional Chinese medicine does not belong to the xin qi deficiency syndrome.

Exclusion Criteria

1. Pregnant and lactating women;
2. People with mental disorders and unwillingness to cooperate;
3. For those who are critically ill, the researcher judges that they cannot persist.

Study & Design

• Study Type: Basic Science
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Analysis of serum metabolome ;Analysis of composition of oral flora;Analysis of composition of intestinal flora;