Glucose II study.
Recruiting
- Conditions
- hypoxia, pulmonary hypertension, COPD, diabetes,
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
Healthy volunteers aged 18-45 with echo evidence of tricuspid regurgitation during systole, which is not clinically relevant but in fact can be demonstrated in most normal individuals.
Exclusion Criteria
1. Obesity (BMI > 30);
2. Presence of medical disease: heart-, lung-, liver-, kidney- and lung disease; diabetes;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Ventilatory response: We will monitor ventilation continuously and afterwards analyze these data based on acute response as well as non linear modeling;<br /><br>2. Pulmonary arterial pressure will be estimated using the tricuspid valve maximum gradient, which is a good estimate of the systolic pulmonary arterial pressure, using echocardiography. We will monitor the PAP every minute for the first 20 minutes and thereafter every 5 minutes.
- Secondary Outcome Measures
Name Time Method Vital and echocardiographic parameters.