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CymaBay Therapeutics, Inc.

CymaBay Therapeutics, Inc. logo
🇺🇸United States
Ownership
Public, Subsidiary
Established
1991-01-01
Employees
101
Market Cap
-
Website
http://www.cymabay.com

Clinical Trials

59

Active:37
Completed:17

Trial Phases

3 Phases

Phase 1:37
Phase 2:15
Phase 3:6

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (58 trials with phase data)• Click on a phase to view related trials

Phase 1
37 (63.8%)
Phase 2
15 (25.9%)
Phase 3
6 (10.3%)

Intended to Determine the Effects of Seladelpar on Normalization of Alkaline Phosphatase Levels in Subjects With Primary Biliary Cholangitis (PBC)

Phase 3
Active, not recruiting
Conditions
Primary Biliary Cholangitis
Interventions
First Posted Date
2023-09-29
Last Posted Date
2025-05-05
Lead Sponsor
CymaBay Therapeutics, Inc.
Target Recruit Count
90
Registration Number
NCT06060665
Locations
🇺🇸

The Institute for Liver Health II LLC dba Arizona Clinical Trials; Arizona Liver Health, Chandler, Arizona, United States

🇺🇸

California Liver Research Institute, Pasadena, California, United States

🇺🇸

University of California (UC) Davis Medical Center, Sacramento, California, United States

and more 40 locations

RESPONSE: Response to Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Control to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Phase 3
Completed
Conditions
Primary Biliary Cholangitis
Interventions
First Posted Date
2020-11-09
Last Posted Date
2024-07-25
Lead Sponsor
CymaBay Therapeutics, Inc.
Target Recruit Count
193
Registration Number
NCT04620733
Locations
🇺🇸

The Institute for Liver Health DBA Arizona Liver Health, Chandler, Arizona, United States

🇺🇸

Arkansas Diagnostic Center, Little Rock, Arkansas, United States

🇺🇸

Stanford University School of Medicine, Palo Alto, California, United States

and more 131 locations

Study Investigating the Safety, Tolerability, and PK, PD, of CB-0406

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Drug: CB-0406 100 mg
Drug: CB-0406 200 mg
Drug: CB-0406 800 mg
Drug: CB-0406 1,000 mg
Drug: Matched placebo
Drug: CB-0406 400 mg
First Posted Date
2020-07-13
Last Posted Date
2021-06-11
Lead Sponsor
CymaBay Therapeutics, Inc.
Target Recruit Count
90
Registration Number
NCT04467684
Locations
🇦🇺

Nucleus Network, Melbourne, Victoria, Australia

ENHANCE: Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and an Inadequate Response to or an Intolerance to Ursodeoxycholic Acid (UDCA)

Phase 3
Completed
Conditions
Primary Biliary Cholangitis
Interventions
First Posted Date
2018-07-27
Last Posted Date
2022-08-02
Lead Sponsor
CymaBay Therapeutics, Inc.
Target Recruit Count
265
Registration Number
NCT03602560
Locations
🇺🇸

Institute for Liver Health, Chandler, Arizona, United States

🇺🇸

Mayo Clinic Arizona - PPDS, Phoenix, Arizona, United States

🇺🇸

The Institute for Liver Health-Tucson, Tucson, Arizona, United States

and more 153 locations

A Study to Evaluate Seladelpar in Subjects With Nonalcoholic Steatohepatitis (NASH)

Phase 2
Terminated
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: Placebos
First Posted Date
2018-06-11
Last Posted Date
2022-09-15
Lead Sponsor
CymaBay Therapeutics, Inc.
Target Recruit Count
181
Registration Number
NCT03551522
Locations
🇺🇸

CymaBay Research Site, Rollingwood, Texas, United States

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