Evaluation of kala basti protocol with Patoladi-ksheera niruha basti and ksheerabala thaila anuvasana basti in Osteoporosis

WHO defines Osteoporosis as “a progressive systemic disease, characterized by low bone density and micro-architectural deterioration in bone that predisposes patients to increased bone fragility and fracturesâ€.According to recent statistics from the International Osteoporosis Foundation, worldwide, 1 in 3 women over the age of 50 years and 1 in 5 men will experience osteoporotic fractures in their lifetime. Every fracture is a sign of another impending one. Moreover, osteoporosis results in a decreased quality of life, increased disability-adjusted life span, and big financial burden to health insurance systems of countries that are responsible for the care of such patients. With an early diagnosis of this disease before fractures occur and by assessing the bone mineral density and with early treatment, osteoporosis can be prevented. It is also important to recognize that the ideal drugs for the treatment of osteoporosis or other bone disorders have yet to be developed. Drugs or therapies which are inexpensive, yet effective with minimal side effects are need of the hour. They must encompass effectiveness to prevent fractures and disease deformities in the enormous number of individuals who will are and will be at risk of bone disease as the population ages. 

Asthi is considered as one among the sapta dhatus and the whole body is dependent on asthi for dharana or stability. Kala is defined as ‘Dhatvashayantara Maryada’ i.e. membranous structure which separates or limits Dhatus and Ashayas. Treatment which is having an effect on kala helps to maintain the normal functioning of the dhatu which is related to it. Pureesha dhara kala/pakwasaya is same as that of asthi dhara kala. Pakwashaya is the vishesha sthana of vata. Vata and asthi are having asraya asryi bhava in a reciprocal way, increase in vata leads to asthi kshaya. Basthi which is considered as ardhachikitsa, act on pakwashaya, thus for diseases of asthi dhatu caused by vata dosha, basti is said to be the primary choice of treatment. Treatment of Asthigata Vikaras is explained as*; Basti* with Ksheera and Ghritha processed with Tikta Dravyas .Patoladi ksheera basti is having tikta dravyas like patola ,arishta , ushira , chaturangula, hribera, rohini, tikta, madana and other drugs like sthira, bala, madhuka, ksheera which are balya, rasayana, and vata shamaka.

       

Initially subjects diagnosed with osteoporosis are screened according to the inclusion and exclusion criteria. Selected patients are  posted for basti line of management for 16 days. Till the next follow up which is on 48th day the subject is given with placebo(starch filled capsule) to keep the subject in touch with the study.

Followup will be done on the 16th and 48th day .