P-POSSUM Score and Length of Stay

Completed

• Conditions: Length of Stay
• Interventions: Other: Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score

• Registration Number: NCT03933137
• Lead Sponsor: Indonesia University

Brief Summary

P-POSSUM score had a predictive power of \>80% to predict the length of stay of kidney transplant recipients

Detailed Description

Not available

Study Timeline

• Study Start: 2018-05-15
• Primary Completion: 2018-08-15
• Study Completion: 2018-10-18
• Status Verified: 2019-04
• Study First Submitted: 2019-04-24
• Study First Submitted QC: 2019-04-27
• Last Update Submitted: 2019-04-27
• Study First Posted: 2019-05-01
• Last Update Posted: 2019-05-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 225

Inclusion Criteria

• Subjects are medical record of recipients who underwent kidney transplant

Exclusion Criteria

• Medical record was incomplete
• Patients who died during surgery or before the patient was discharged.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Not prolonged length of stay	Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score	Living donor patients who had ≤ 6 days length of stay after laparoscopic nephrectomy procedure
Prolonged length of stay	Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (P-POSSUM) score	Living donor patients who had \> 6 days length of stay after laparoscopic nephrectomy procedure

Primary Outcome Measures

Name	Time	Method
P-POSSUM score Discrimination	1 day before surgery until discharged from hospital, up to 30 days	P-POSSUM score ability to discriminate length of stay based on variable scores: physical parameters and operative parameters
P-POSSUM score Calibration	1 day before surgery until discharged from hospital, up to 30 days	P-POSSUM score cutoff to predict length of stay based on variable scores: physical parameters and operative parameters
Correlation between each variable of P-POSSUM and length of stay	1 day before surgery until discharged from hospital, up to 30 days	Correlation between 18 variables (12 variables as physical parameters and 6 variables as operative parameters) and length of stay

Secondary Outcome Measures

Name	Time	Method
Patient's length of stay post kidney transplantation	From post surgery until discharged from hospital, up to 30 days	Patient's length of stay post kidney transplantation
P-POSSUM score (physical parameters): Lung disease	1 day before surgery	The score for lung disease variable cut-off: 1. point for no dyspnea; 2. points for exertional dyspnea or mild COPD on CXR; 4 points for limiting dyspnea or moderate COPD on CXR 8 points for dyspnea at rest or fibrosis/consolidation on CXR
P-POSSUM score (physical parameters): Heart disease	1 day before surgery	The score for heart disease variable cut-off: 1. point for no heart failure; 2. point for diuretic, digoxin or angina/hypertension medicine usage; 4 point for peripheral edema, warfarin, or borderline cardiomegaly on chest X-ray (CXR)
P-POSSUM score (physical parameters): ECG abnormality	1 day before surgery	The score for ECG abnormality variable cut-off: 1 point for normal ECG 4 points for atrial fibrillation (HR 60-90 8 points for 5 ectopic beats/min, Q waves or ST/T wave change
P-POSSUM score (physical parameters): Systolic blood pressure	1 day before surgery	The score for systolic blood pressure variable cut-off: 1. point for 110 - 130 mmHg; 2. points for 100-109 mmHg or 131-170 mmHg; 4 points for \> 170 mmHg or 90-99 mmHg 8 points for \< 90 mmHg
P-POSSUM score (physical parameters): Pulse rate	1 day before surgery	The score for pulse rate variable cut-off: 1. point for 50-80 beats per minute (bpm); 2. points for 40-59 bpm or 81-100 bpm; 4 points for 101-120 bpm 8 points for \> 121 bpm or \< 40 bpm
P-POSSUM score (physical parameters): Hemoglobin	1 day before surgery	The score for hemoglobin variable cut-off: 1. point for 13-16 g/dL; 2. points for 11.5-12.9 or 16.1-17 d/dL; 4 points for 10-11.4 or 17.1-18 g/dL 8 points for \<10 or \>18 g/dL
P-POSSUM score (physical parameters): Leukocyte count	1 day before surgery	The score for leukocyte count variable cut-off: 1. point for 4.000-10.000/mm3; 2. points for 10.100-20.000 atau 3.100-4.000/mm3; 4 points for \>20.000 atau \<3.000/mm3
P-POSSUM score (physical parameters): Plasma potassium concentration	1 day before surgery	The score for plasma potassium concentration variable cut-off: 1. point for 3.5-5 mmol/L; 2. points for 3.2-3.4 or 5.1-5.3 mmol/L; 4 points for 2.9-3.1 or 5.4-5.9 mmol/L 8 points for \<2.9 or \>5.9 mmol/L
P-POSSUM score (physical parameters): Age	1 day before surgery	The score for Age variable cut-off: 1. point for \<61 years; 2. point for 61-71 years; 4 point \>71 years
P-POSSUM score (physical parameters): Plasma sodium concentration	1 day before surgery	The score for plasma sodium concentration variable cut-off: 1. point for \>135 mmol/L; 2. points for 131-135 mmol/L; 4 points for 126-130 mmol/L 8 points for \<126 mmol/L
P-POSSUM score (operative parameters): Peritoneal contamination/soiling	Intraoperative	The score for peritoneal contamination/soiling variable cut-off: 1. point for none; 2. points for minor (serous fluid); 4 points for local pus 8 points for free bowel content, pus or blood
P-POSSUM score (operative parameters): Number of procedures	1 day before surgery	The score for number of procedures variable cut-off: 1 point for one 4 points for two 8 points for more than two
P-POSSUM score (operative parameters): Presence of malignancy	1 day before surgery	The score for presence of malignancy variable cut-off: 1. point for none; 2. points for primary only; 4 points for nodal metastases 8 points for distant metastases
P-POSSUM score (operative parameters): Mode of surgery	1 day before surgery	The score for mode of surgery variable cut-off: 1 point for elective 4 points for emergency resuscitation of \> 2 hours possible operation \< 24 hours after admission 8 points for emergency (immediate surgery \< 2 hours needed)
P-POSSUM score (operative parameters): Intraoperative blood loss	Intraoperative	The score for intraoperative blood loss variable cut-off: 1. point for \<100 mL; 2. points for 101-500 mL; 4 points for 501-999 mL 8 points for \> 999 mL

Trial Locations

Locations (1)

Rumah Sakit Cipto Mangunkusumo; 🇮🇩 Jakarta Pusat, DKI Jakarta, Indonesia