Mutational analysis in Gastrointestinal Stromal tumour (GIST)
Not Applicable
- Conditions
- Health Condition 1: C189- Malignant neoplasm of colon, unspecifiedHealth Condition 2: C19- Malignant neoplasm of rectosigmoidjunctionHealth Condition 3: C20- Malignant neoplasm of rectumHealth Condition 4: C179- Malignant neoplasm of small intestine, unspecifiedHealth Condition 5: C169- Malignant neoplasm of stomach, unspecified
- Registration Number
- CTRI/2024/01/061244
- Lead Sponsor
- Dr Antara Sanyal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1 Newly diagnosed case of GIST
2 Treatment naïve
Diagnosis will be based upon the morphology and immunophenotype of the primary followed by mutational analysis
Exclusion Criteria
1 Consent refusal
2 Patients with inadequate sample in tissue biopsy
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the mutation pattern at baseline and follow-up patients with newly diagnosed GISTs <br/ ><br>Timepoint: 3 months 6 months 9 months 12 months
- Secondary Outcome Measures
Name Time Method To audit retrospective data for mutational analysis profile clinicopathological findings & OS over a period of 5 years (2017-2022). <br/ ><br>PFS & OS will be prospectively observed in patient cohort <br/ ><br>Timepoint: Baseline, 3 months, 6 months, 9 months, 12 months