se of NIRS during mechanical thrombectomy for ischaemic stroke
Completed
- Conditions
- Ischaemic stroke, Intra-arterial thrombectomy, Near infrared spectroscopy Ischemische beroerte, intra-arteriële trombectomie, bijna infrarode spectroscopie
- Registration Number
- NL-OMON25450
- Lead Sponsor
- niversity Medical Center Groningen, department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Equal or above 18 years of age
-An ischemic stroke caused by a proximal arterial occlusion of the MCA
Exclusion Criteria
- Consent is not given by patient or his/her legal representative.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Periprocedural cerebral oxygenation of the ischemic and non-ischemic hemisphere; specifically:<br /><br>- Before and after the induction of anaesthesia<br /><br>- Before and after the thrombectomy (reperfusion)<br /><br>- Before and after the end of anaesthesia<br /><br>2. Neurological outcome quantified by:<br /><br>- NIHHS score
- Secondary Outcome Measures
Name Time Method 1. Demographic parameters<br /><br>2. Radiological imaging:<br /><br>- Location of the vascular occlusion and the level of collateral vasculature<br /><br>- Modified Thrombolysis In Cerebral Infarction (mTICI)-score after thrombectomy<br /><br>- Physiological and pharmacological variables before, during and after the procedure<br /><br>- Physiological variables: Heart rate, invasive blood pressure, non-invasive blood pressure, FiO2, CO2, arterial haemoglobin saturation, EEG measure (if used) <br /><br>- Pharmacological variables: drugs used, doses and concentrations administered<br>