Respiratory Monitoring During Right Heart Catheterization to Differentiate Between Various Types of Pulmonary Hypertension; The Effects of the Cardiovascular System on the Lung Mechanical Properties
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Respiratory flow
研究概览
简要总结
Respiratory monitoring during right heart catheterization to differentiate between various types of pulmonary hypertension; The effects of the cardiovascular system on the lung mechanical properties.
详细描述
Differentiation between different kinds of pulmonary hypertension (PHTN) requires right heart catheterization. Monitoring heart failure patients is challenging in many. The study will enroll patients undergoing right heart catheterization (RHC) for the evaluation of heart failure and PHTN, based on the regular clinical practice. The regular indices as the right ventricle pressure (RVP), pulmonary artery pressure (PAP), pulmonary artery wedge pressure (PAWP), and cardiac output will be measured with the Swan Ganz Catheter and recorded.
Noninvasive measurement of the respiratory flow will be acquired by a medical approved flow-meter that is mounted on a simple plastic breathing mask.
Non-invasive system that includes three accelerometers that are attached to the chest and epigastrium of the patient will be used to measure respiratory chest wall dynamics.
Through evaluating the correlation between the invasive and non-invasive measurements the study intends to prove the ability of the non-invasive system to provide the required information.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing right heart catheterization
排除标准
- •Inability or unwillingness to follow or to sign the study protocol.
结局指标
主要结局
Respiratory flow
时间窗: only during the procedure of right heart catheterization
ml units
Pulmonary artery pressure
时间窗: only during the procedure of right heart catheterization
In mmHg measured by Swan-Ganz catheter
Chest wall acceleration
时间窗: only during the procedure of right heart catheterization
local tidal displacement
次要结局
- Pulmonary artery wedge pressure(only during the procedure of right heart catheterization)
- Right ventricle pressure(only during the procedure of right heart catheterization)
研究者
yair feld MD
Principal investigator
Rambam Health Care Campus
