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临床试验/NCT03061669
NCT03061669Unknown不适用

Respiratory Monitoring During Right Heart Catheterization to Differentiate Between Various Types of Pulmonary Hypertension; The Effects of the Cardiovascular System on the Lung Mechanical Properties

Rambam Health Care Campus1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2017年2月26日最近更新:
适应症

试验速览

阶段
不适用
入组人数
200
试验地点
1
主要终点
Respiratory flow

研究概览

简要总结

Respiratory monitoring during right heart catheterization to differentiate between various types of pulmonary hypertension; The effects of the cardiovascular system on the lung mechanical properties.

详细描述

Differentiation between different kinds of pulmonary hypertension (PHTN) requires right heart catheterization. Monitoring heart failure patients is challenging in many. The study will enroll patients undergoing right heart catheterization (RHC) for the evaluation of heart failure and PHTN, based on the regular clinical practice. The regular indices as the right ventricle pressure (RVP), pulmonary artery pressure (PAP), pulmonary artery wedge pressure (PAWP), and cardiac output will be measured with the Swan Ganz Catheter and recorded.

Noninvasive measurement of the respiratory flow will be acquired by a medical approved flow-meter that is mounted on a simple plastic breathing mask.

Non-invasive system that includes three accelerometers that are attached to the chest and epigastrium of the patient will be used to measure respiratory chest wall dynamics.

Through evaluating the correlation between the invasive and non-invasive measurements the study intends to prove the ability of the non-invasive system to provide the required information.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients undergoing right heart catheterization

排除标准

  • Inability or unwillingness to follow or to sign the study protocol.

结局指标

主要结局

Respiratory flow

时间窗: only during the procedure of right heart catheterization

ml units

Pulmonary artery pressure

时间窗: only during the procedure of right heart catheterization

In mmHg measured by Swan-Ganz catheter

Chest wall acceleration

时间窗: only during the procedure of right heart catheterization

local tidal displacement

次要结局

  • Pulmonary artery wedge pressure(only during the procedure of right heart catheterization)
  • Right ventricle pressure(only during the procedure of right heart catheterization)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

yair feld MD

Principal investigator

Rambam Health Care Campus

研究点 (1)

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