Effects of Loaded Breathing Training on Blood Pressure in Essential Hypertensive Patients
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Home blood pressure
研究概览
简要总结
The purpose of this study is to determine whether adding load to slow controlled breathing training could enhance blood pressure lowering in patients with essential hypertension.
详细描述
Hypertension (HT) is one of the major risk of cardiovascular diseases and cost of pharmacological treatment is a very high. Lifestyle modification is the first trial in stage 1 hypertension before commencing pharmacological treatment and a co-treatment with drug in hypertensive patient. Slow paced breathing training and physical training has been shown to reduce both systolic and diastolic blood pressure in HT. Moreover loaded breathing was reported to be able to decrease blood pressure in healthy. Loaded slow breathing training may enhance the antihypertensive effect of slow paced breathing.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 35 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of essential hypertension stage I-II
排除标准
- •Respiratory disease
- •Diabetes mellitus
- •Heart disease
- •Renal disease
- •Cerebrovascular disease
- •Dyslipidemia
- •Pregnancy
研究组 & 干预措施
control
The patients in this control group do not conduct any breathing training.
ULB
The patients conduct controlled slow breathing training using the WPTB device without inspiratory resistance.
干预措施: ULB , LB (Device)
LB
The patients breath in against resistance using WPTB device.
干预措施: ULB , LB (Device)
结局指标
主要结局
Home blood pressure
时间窗: Pre- and post - 8 weeks of intervention at rest
次要结局
- Office blood pressure(Pre- and post- 8 weeks of intervention at rest)
- Exercising blood pressure(Blood pressure during exercise at pre- and post-8 weeks of intervention)
- Heart rate variability(Heart rate variability at pre-and post- 8 weeks of intervention)
研究者
Benjarat Sangthong
Faculty of associated medical science
Khon Kaen University