A Randomised Controlle Study of Vaginal Bromocriptine and Oral Carbegoline in treating Hyperprolacrinemia among women Attending Infertility Clinic in Abuth
Not Applicable
- Conditions
- Fertility-female
- Registration Number
- PACTR202105785593643
- Lead Sponsor
- Irshad Asma
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
1.Infertile women with hyperprolactinemia confirmed by measuring fasting serum prolactin levels.
2.Women who give informed consent to participate in the study.
3.Women who are motivated to comply with study requirements including clinic visits, repeated blood sampling, vaginal drug administration and timely use of medication.
Exclusion Criteria
1.Women with space occupying lesions or other complications requiring urgent intervention.
2.Women with active genital tract infections or cancers.
3.Renal or hepatic insufficiency.
4.Women who were already on treatment at the time of the study.
5.Women who were unable to provide informed consent.
6.Women with allergies to any component of the drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Percentage fall in serum prolactin levels during treatment in both arms of the study.<br>2.Proportion of women who experience side-effects in both arms of the study.<br>
- Secondary Outcome Measures
Name Time Method 1.Proportion of women in both arms who achieve symptom relief following treatment.