Combination of Lymphatico-venular Anastomosis and Liposuction to Treat Cancer-related Lymphedema

Recruiting

• Conditions: Description of an Effective Surgical Strategy to Treat Cancer-related Lymphedema; Combination of LVA and Liposuction Guarantees Long Lasting Results
• Interventions: Procedure: combination of lymphaticovenular anastomosis and liposuction

• Registration Number: NCT05025982
• Lead Sponsor: University of Siena

Brief Summary

* cooperation of an International team with many years of experience in surgical management of lymphedema

* description of an effective surgical strategy to treat cancer-related lymphedema, a high incidence pathology

* the combination of LVA and liposuction guarantees long lasting results

Detailed Description

Cancer-related lymphedema represents one of the major complications of cancer treatment, especially for breast and gynecologic cancers. Moreover, it has high impact on cancer survivors and healthcare systems. Lymphedema management still remains challenging. The better understanding of lymphedema physiopathology as well as the development of sophisticated surgical and diagnostic techniques have led to effective strategies to address lymphedema patients but, despite the considerable interest in international literature, no consensus exist. The combination of LVA and liposuction may represent an effective strategy in treating patients with cancer-related lymphedema, in order to reach a significant decrease in volume and reduction of lymphangitis rate as well as stable results in time. In addition, it has the aim of being minimally invasive and well tolerated by patients

Study Timeline

• Study Start: 2018-08-01
• Study First Submitted: 2021-04-28
• Status Verified: 2021-08
• Study First Submitted QC: 2021-08-26
• Last Update Submitted: 2021-08-26
• Study First Posted: 2021-08-30
• Last Update Posted: 2021-08-30
• Primary Completion: 2025-05-01
• Study Completion: 2025-05-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

patients affected by secondary lymphedema

• free from cancer disease

Exclusion Criteria

• persistence of the neoplastic pathology

• patients affected by primary lymphedema

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group of partecipants	combination of lymphaticovenular anastomosis and liposuction	we combined two surgical techniques in the same group of patients

Primary Outcome Measures

Name	Time	Method
change in volume	one year	change in volume of the limb affected by cancer-related lymphedema

Trial Locations

Locations (1)

Guido Gabriele; 🇮🇹 Siena, Italy