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Clinical Trials/CTRI/2023/01/049278
CTRI/2023/01/049278
Not yet recruiting
Phase 4

Comparison of Airway Pressure Release Ventilation versus Pressure Regulated Volume Control mode of ventilation in the exploratory laparotomy patients in intensive care unit

Director Principal0 sites0 target enrollmentTBD

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Not specified
Sponsor
Director Principal
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
3 years ago
Study Type
Interventional

Investigators

Eligibility Criteria

Inclusion Criteria

  • 1\. Patients on invasive mechanical ventilation and admitted in ICU following exploratory Laparotomy due to acute respiratory failure (ARF) for less than 24 hours
  • 2\. Age group 18\-60 years
  • 3\. Stable hemodynamic parameters (Mean Arterial Pressure between 70 mm Hg and 100 mm Hg, heart rate between 60 and 100/minute, SPO2 \>\= 90%)
  • 4\. Richmond Agitationâ??Sedation Scale (RASS) between 0 and \-2

Exclusion Criteria

  • 1\. Pregnant and morbidly obese patients (BMI \>35\)
  • 2\. Patient diagnosed with acute respiratory distress syndrome (ARDS) (Mild, Moderate, or Severe) according to Berlinâ??s definition.
  • 3\. Patients with severe or chronic heart, lung, hepatic or renal disease
  • 4\. Patients with severe neuromuscular disorders
  • 5\. Patient on vasopressors, cardiac depressants or neuromuscular blockers
  • 6\. Patient with traumatic brain injury
  • 7\. Patient with blunt or traumatic chest injury
  • 8\. Patients with severe multiple organ dysfunction.

Outcomes

Primary Outcomes

Not specified

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