Frontal QRS-T Angle as an Electrocardiographic Marker for Collateral Circulation in Coronary Artery Chronic Total Occlusion
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Assiut University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- correlation between frontal QRS-T angle and collateral circulation in CTO patients
Study Overview
Brief Summary
• Aim of the work: To examine the relationship between collateral circulation and the frontal QRS-T angle in patients with chronic total occlusion (CTO)
Detailed Description
i. Study Objectives
- Primary Objective:
• To examine the relationship between coronary collateral circulation and the electrocardiographic frontal QRS-T angle in patients diagnosed with chronic total occlusion (CTO). 2. Secondary Objectives:
- To identify other independent clinical and laboratory predictors (such as serum albumin levels and neutrophil counts) associated with an increased frontal QRS-T angle in patients with CTO.
- To compare echocardiographic parameters (such as left ventricular ejection fraction and left ventricular dimensions) between patients with a normal QRS-T angle and those with an increased QRS-T angle.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients undergoing diagnostic coronary angiography due to stable angina persisting for a minimum duration of three months.
- •Patients diagnosed with total occlusion in at least one coronary artery, assessed to have chronic total occlusion (CTO) based on clinical and angiographic findings.
Exclusion Criteria
- •Patients presenting with malignancies, atrial fibrillation, connective tissue disorders, hepatic failure, or renal failure.
- •A documented history of cardiac pacemaker implantation, prior bypass surgeries, or surgical valve replacements.
- •Congenital heart anomalies.
- •Patients receiving pharmacological interventions that affect ventricular repolarization (other than beta-adrenergic antagonists).
- •Individuals exhibiting abnormal electrolyte levels at the time of admission.
Arms & Interventions
Increased QRS-T Angle
Subjects exhibiting an increased frontal QRS-T angle (≥110° for men, >90° for women).
Intervention: 12-lead Electrocardiogram (ECG) and Coronary Angiography (Diagnostic Test)
Normal QRS-T Angle
Subjects presenting with a normative frontal QRS-T angle (<110° for men, <90° for women).
Intervention: 12-lead Electrocardiogram (ECG) and Coronary Angiography (Diagnostic Test)
Outcomes
Primary Outcomes
correlation between frontal QRS-T angle and collateral circulation in CTO patients
Time Frame: baseline ( at the time of the diagnosis )
• To examine the relationship between coronary collateral circulation and the electrocardiographic frontal QRS-T angle in patients diagnosed with chronic total occlusion (CTO).
Secondary Outcomes
No secondary outcomes reported
Investigators
Tarek Yaser Fathi
Resident Physician
Assiut University