A randomised controlled trial of the benefits of exercise early in the management of Type 2 diabetes

niversity of Bristol (UK)0 个研究点目标入组 593 人开始时间: 2005年7月25日最近更新: 2022年5月2日

试验速览

2011 Results article in http://www.ncbi.nlm.nih.gov/pubmed/21705068 2014 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/24811615 Effect on inflammatory markers 2018 Other publications in https://www.ncbi.nlm.nih.gov/pubmed/29386030 Qualitative analysis of motivation 2022 Other publications in https://pubmed.ncbi.nlm.nih.gov/35430794/ Analysis of association of glycaemic control with diet independent of weight change (added 19/04/2022)

•This a multicentre trial recruiting 750 participants from across the South West of England. Individuals must satisfy the following criteria before they can be considered eligible:
•1. Type 2 diabetes mellitus (T2DM) as defined by: body mass index (BMI) >25, no ketosis, no significant weight loss prior to diagnosis, aged above 30 at diagnosis
•2. Between 5 and 8 months from clinical diagnosis of T2DM

•1. Age over 80 at diagnosis
•2. HbA1c of greater than 10%
•3. Blood pressure greater than 180/100
•4. Low-density lipoprotein (LDL) greater than 4
•5. Patients already receiving a maximum dose of a sulphonylurea
•6. Have a current diagnosis of unstable angina
•7. Have had a myocardial infarction within the previous three months
•8. Unable to increase their physical activity
•9. Subject is pregnant or is of childbearing age and not surgically sterile, 2 years postmenopausal or does not practice one method of contraception

发起方

niversity of Bristol (UK)