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Clinical Trials/NCT01083134
NCT01083134
Unknown
Not Applicable

The Correlation of Heart Hemodynamic Status Between 320 Multidetector Computed Tomography, Echocardiography and Cardiac Catheterization in Patients With Coronary Artery Disease

Chang Gung Memorial Hospital1 site in 1 country100 target enrollmentMarch 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Coronary Artery Disease
Sponsor
Chang Gung Memorial Hospital
Enrollment
100
Locations
1
Primary Endpoint
all cause mortality
Last Updated
11 years ago

Overview

Brief Summary

With the advances in multidetector computed tomography (MDCT) technology, CT angiography (CTA) of the coronary arteries using 64-slice or dual-source CT systems has evolved into a robust, alternative, noninvasive imaging technique to rule out coronary artery disease (CAD). Reported sensitivities and specificities of coronary CTA can compete with those of catheter angiography.

Because CT is the major source of ionizing radiation in medicine, dual isotope myocardial perfusion scintigraphy and coronary CTA 16-, 64-slice MDCT and DSCT scanners are associated with the highest amount of radiation dose. Recently, a new generation of MDCT machines with even more detector row (320) has become clinically available. The maximum detector width of 16 cm enables the entire heart to be examined in a single rotation and within a single heartbeat and is expected to substantially reduce artifacts from breathing and body motion. Due to high volume coverage, 320-slice CT machines are able to perform a nonspiral, ECG-gated examination of the heart within a single breath-hold.

The purpose of this study was to investigate the correlation of hemodynamic status of 320 MDCT, echocardiography, and coronary catheterization in patients who suspected coronary artery disease.

Registry
clinicaltrials.gov
Start Date
March 2010
End Date
March 2020
Last Updated
11 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Chang Gung Memorial Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Intermediate or high risk for coronary artery disease
  • Healthy volunteers

Exclusion Criteria

  • Unstable angina
  • Acute myocardial infarction
  • Active cancer status
  • Renal failure(Creatinine \> 1.5 mg/dl)
  • Contrast allergy history

Outcomes

Primary Outcomes

all cause mortality

Time Frame: one year

Study Sites (1)

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