Comparison of Cardiac Computed Tomography for the Detection of Coronary Artery Disease With Nuclear Stress Test
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Calcium score
研究概览
简要总结
To compare the efficacy of 16-row multi-detector CT (MDCT) with standard myocardial perfusion imaging in detecting coronary artery disease (CAD) in patients without a previously established diagnosis of CAD.
详细描述
Nuclear stress testing is currently the established non-invasive modality in detecting flow-obstructing coronary artery disease (CAD).
Recently, multi-detector CT (MDCT) has emerged as a new modality that offers a non-invasive means to directly visualize coronary anatomy and any CAD. Studies have shown that MDCT has excellent sensitivity and a high negative predictive value in detecting significant CAD.
The purpose of this study is to compare MDCT with nuclear stress testing for detecting CAD in previously undiagnosed patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Referred for a clinical indicated stress SPECT MPI
- •Adequate IV access in both arms
排除标准
- •History of coronary angioplasty or stent placement
- •History of coronary bypass surgery
- •Angiographic history of flow-limiting CAD
- •Documented history of elevated cardiac markers
- •Documented history of injury or infarct on ECG
- •Absence of sinus rhythm
- •Current history of renal insufficiency
- •Known allergy to contrast dye
结局指标
主要结局
Calcium score
时间窗: 1 year
次要结局
未报告次要终点
研究者
Wen-Chih Wu
Staff Cardiologist
Providence VA Medical Center