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临床试验/NCT05861726
NCT05861726尚未招募不适用

Effects Of a Single Bout Of Acute Aerobic Exercise On Executive Brain Functions Of Young Adults: A Randomized Control Trial

Khyber Medical College, Peshawar0 个研究点目标入组 38 人开始时间: 2023年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
38
主要终点
Change in performance of "N-Back task/2-Back task " before & after an acute session of aerobic exercise.

研究概览

简要总结

We are comparing higher cerebral functions including cognitive flexibility, inhibitory control and working memory in healthy young adults between a group of acute aerobic exercise and a control group.

详细描述

The objective of this study is to compare cognitive flexibility, inhibitory control, and working memory in healthy young adults between two groups: a group undergoing acute aerobic exercise and a control group.

Methodology:

Study Design: A Randomized Controlled Trial Study Setting: The Physiology Laboratory at Khyber Medical College, Peshawar Study Duration: The study will last for three months. Sample Size: The study will include 19 participants in each group - the Exercising group (E-Group) and the Control group (C-Group).

Healthy young people between 18-25 years who are non-smokers will be included. Sampling: The enrollment in the Randomised Control Trial will be conveniently based, wherein all those who meet the inclusion and exclusion criteria will be enrolled as per study numbers. A lottery method will be adopted for randomization.

Procedure:

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Healthy young adults

排除标准

  • •cardiorespiratory disorders
  • •psychiatric disorders

研究组 & 干预措施

Exercising Group

Active Comparator

The exercising group shall have pre-intervention assessment of executive brain functions vide Stroop test, Trail making test & N-Back task/2-Back by using online psytoolkit followed by intervention.

The intervention for the group being acute aerobic exercise, which will comprise of 30 minutes of treadmill walking at 60-65% of Heart Rate max with continuous recording of heart rate and ECG via Biopac MP36 Student Lab system.

This will be followed by post-intervention assessment of executive brain functions vide Stroop test, Trail making test & N-Back task/2-Back by using online psytoolkit.

干预措施: Aerobic exercise (Behavioral)

Control Group

Placebo Comparator

The control group will also have pre-intervention assessment of executive brain functions vide Stroop test, Trail making test & N-Back task/2-Back by using online psytoolkit.

The control group will undergo NO EXERCISE intervention. They will sit idly in laboratory for 30 minutes with continuous recording of heart rate and ECG via Biopac system.

The executive brain functions of the control group will be re-assessed vide Stroop test, Trail making test & N-Back task/2-Back by using online psytoolkit.

干预措施: None (control group) (Other)

结局指标

主要结局

Change in performance of "N-Back task/2-Back task " before & after an acute session of aerobic exercise.

时间窗: Change in the number of false alarms 5 minutes before and 3 minutes after an acute session of aerobic exercise will be recorded

"N-Back task/2-Back task" test will be used to assess the working memory aspect of "executive brain functions". The number of false alarms on the test will be measured.

Change in performance of Stroop Test before & after an acute session of aerobic exercise

时间窗: Change in the reaction time of stroop test 5 minutes before and 3 minutes after aerobic exercise will be recorded

Stroop test will be used to assess cognitive flexibility aspect of "executive brain functions". The reaction time in milliseconds to identify the congruent and incongruent words in the stroop test will be measured.

Change in performance of "Stop Signal Task Test" before & after an acute session of aerobic exercise.

时间窗: Change in status of the response 5 minutes before and 3 minutes after aerobic exercise will be recorded

"Stop signal task" test will be used to assess the inhibitory control aspect of "executive brain functions". Status of the response(1=correct, 2=wrong, 3=timeout) will be measured in the test.

Change in performance of "Stop Signal Task Test" before & after an acute session of aerobic exercise.

时间窗: Change in the response time 5 minutes before and 3 minutes after aerobic exercise will be recorded

"Stop signal task" test will be used to assess the inhibitory control aspect of "executive brain functions". The response time in milliseconds will be measured in the test.

Change in performance of "N-Back task/2-Back task " before & after an acute session of aerobic exercise.

时间窗: Change in reaction time 5 minutes before and 3 minutes after an acute session of aerobic exercise will be recorded

"N-Back task/2-Back task" test will be used to assess the working memory aspect of "executive brain functions". The reaction time taken in milliseconds to correctly match target letters in the test will be measured.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

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