Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Body Mass Index Quantitative Trait Locus 7 Disorder
- Sponsor
- Isfahan University of Medical Sciences
- Enrollment
- 50
- Locations
- 1
- Primary Endpoint
- the amount of weight reduction in two dietary groups
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.
Detailed Description
Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD) risk factors have reported contradictory results. Objective: In present study, the investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children. Design: In this randomized controlled trial, the investigators recruited 50 overweight and obese women, aged 6-11years into HP or control energy restricted diets for 10 weeks (protein, carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount, divided to animal and plant sources in 50%-50% and animal sources distributed (half/half) between meats and dairy products. Fasting blood samples, lipid profile, systolic and diastolic blood pressure and anthropometric measurements were measured based on the standard guidelines.
Investigators
Leila Azadbakht
Isfahan University of Medical Sciences
Isfahan University of Medical Sciences
Eligibility Criteria
Inclusion Criteria
- •BMI \> 85th age of 6-11 years
- •no history of chronic diseases
- •no taken medications
Exclusion Criteria
- •do not prescribe their diet
- •mental retardation
Outcomes
Primary Outcomes
the amount of weight reduction in two dietary groups
Time Frame: 10 weeks
weight reduction (kg)
Secondary Outcomes
- LDL (mg/ml)(10 weeks)
- HDL (mg/ml)(10 weeks)
- fasting blood glucose(10 weeks)
- total cholesterol (mg/dl)(10 weeks)
- blood pressure(10 weeks)