Effect of High Protein Diet on Cardiovascular Diseases Risk Factors Among Overweight and Obese Children
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- the amount of weight reduction in two dietary groups
研究概览
简要总结
The investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.
详细描述
Background: Studies regarding the effects of high protein (HP) diet on cardiovascular (CVD) risk factors have reported contradictory results.
Objective
In present study, the investigators aimed to determine the effects of HP diet on CVD risk factors among overweight and obese children.
Design: In this randomized controlled trial, the investigators recruited 50 overweight and obese women, aged 6-11years into HP or control energy restricted diets for 10 weeks (protein, carbohydrate, fat: 25%, 45%, 30% vs. 15%, 55%, 30%, respectively). Total protein amount, divided to animal and plant sources in 50%-50% and animal sources distributed (half/half) between meats and dairy products. Fasting blood samples, lipid profile, systolic and diastolic blood pressure and anthropometric measurements were measured based on the standard guidelines.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 6 Years 至 11 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI > 85th age of 6-11 years
- •no history of chronic diseases
- •no taken medications
排除标准
- •do not prescribe their diet
- •mental retardation
结局指标
主要结局
the amount of weight reduction in two dietary groups
时间窗: 10 weeks
weight reduction (kg)
次要结局
- LDL (mg/ml)(10 weeks)
- HDL (mg/ml)(10 weeks)
- fasting blood glucose(10 weeks)
- total cholesterol (mg/dl)(10 weeks)
- blood pressure(10 weeks)
研究者
Leila Azadbakht
Isfahan University of Medical Sciences
Isfahan University of Medical Sciences