The effect of Atracurium and Cis-Atracurium injection on hemodynamic status and Neutrophil-to-Lymphocyte Ratio (NLR) during anesthesia inductio
Phase 2
- Conditions
- Change in hemodynamic status and NLR.
- Registration Number
- IRCT20160307026950N48
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Patients 18 to 65 years old
Anesthesia class I and II according to ASA criteria
Candidate for anesthesia with Atracurium and Cis-Atracurium
Informed consent to enter the study
Exclusion Criteria
Obesity or BMI (Body Mass Index) of more than 30
History of cardiovascular diseases and hemodynamic disorders or myocardial infarction in the last 6 months
Taking psychoactive drugs, antihistamines and corticosteroids in the last week
Addiction to opioid and non-opioid drugs
Pregnancy and breastfeeding
Having diabetes, orthostatic hypotension, bradycardia, hypokalemia, hypothyroidism, depression, long QT syndrome, asthma and allergies
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Heart Rate. Timepoint: before induction of anesthesia and at 3, 10, and 20 minutes after anesthesia. Method of measurement: Electrocardiogram.;Blood Pressure. Timepoint: before induction of anesthesia and at 3, 10, and 20 minutes after anesthesia. Method of measurement: Sphygmomanometer.;Oxygen saturation. Timepoint: before induction of anesthesia and at 3, 10, and 20 minutes after anesthesia. Method of measurement: Pulse Oximeter.;Neutrophil to lymphocyte ratio. Timepoint: before induction of anesthesia and at 3, 10, and 20 minutes after anesthesia. Method of measurement: Cell count of venous blood sample.
- Secondary Outcome Measures
Name Time Method