A randomized, double-blind, double dummy study comparing polyp size reduction of corticosteroid nasal irrigations with nasal sprays in chronic rhinosinusitis with nasal polyp
Phase 3
- Conditions
- asal polyp patient need effective topical corticosteroid method for control disease.corticosteroid nasal irrigations, nasal sprays, nasal polyp
- Registration Number
- TCTR20210604009
- Lead Sponsor
- Faculty of Medicine, Prince of Songkla University,
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 98
Inclusion Criteria
Bilateral nasal polyp patient
Exclusion Criteria
1. Previous sinus surgery.
2. Used systemic corticosteroid before 2 weeks, Nasal steroid before 4 weeks, Nasal decongestant before 1 day.
3. Bacterial /Viral/ Fungal rhinosinusitis patient.
4.Patient with systemic conditions Ex. immunodeficiency, autoimmune diseases, cystic fibrosis, mucociliary disorders
5. Patient with pulmonary tuberculosis, DM (uncontrol; Random plasma glucose>200 mg/dL).
6. Patient with severe deviated nasal septum.
7. Patient with steroid allergy, glaucoma.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method asal polyp size within one month after end of the intervention Nasal polyp grading(0-3)
- Secondary Outcome Measures
Name Time Method asal symptom score within one month after end of the intervention Patient reported outcome using a questionnaire interview