Survival and PN Dependence in SBS Patients
- Conditions
- Short Bowel Syndrome
- Registration Number
- NCT06102668
- Lead Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
- Brief Summary
Short bowel syndrome (SBS) is a rare condition resulting from the loss of portions of the small intestine, and can cause a spectrum of metabolic and physiologic disturbances.The objective of this study was to determine the longterm survival and parenteral nutrition dependence of adult patients with SBS.
- Detailed Description
Short bowel syndrome (SBS), the most common form of intestinal failure, is a rare condition resulting from the loss of portions of the intestine, typically because of extensive surgical resection or loss of intestinal function. Patients with SBS often stuffer from intestinal insufficiency or intestinal failure because they are unable to maintain fluid and nutrient balances on a normal diet. SBS can cause various metabolic and physiologic disturbances. Although parenteral nutrition is a life-saving measure for many patients with SBS, patients with SBS is associated with decreased survival and parenteral nutrition (PN) dependence. Few studies have reported the survival and PN dependence in adult SBS patients in China.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 173
- Adult patients diagnosed with SBS.
- age <18 years; patients with active malignant tumors.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Survival 2012/1/1-2019/1/1 Survival rate in patients with SBS
Parenteral nutrition dependence 2012/1/1-2019/1/1 Parenteral nutrition dependence in patients with SBS
- Secondary Outcome Measures
Name Time Method Risk factors 2012/1/1-2019/1/1 Risk factors of mortality and parenteral dependence in patients with SBS
Cause of death 2012/1/1-2019/1/1 Cause of death in patients with SBS at the end of follow-up