Survey of QRS Frequency at Various Left Ventricular Pacing Sites for Cardiac Resynchronization
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 14
- 试验地点
- 1
- 主要终点
- QRS Frequency at Each Paced Location
研究概览
简要总结
LV pacing at various sites with recording of ECG and subsequent signal analysis at different sites.
详细描述
During routine cardiac resynchronization pacemaker or implantable defibrillator (ICD) implantation (including de-novo and upgrade from standard device, additional pacing within 3 different coronary veins will be performed in combination with a previously implanted right ventricular pacing or ICD lead. The resulting electrocardiogram signal will be analyzed afterwards. A time-frequency analysis (TFA) of several ECG leads at each paced site will be performed and compared. The results of the TFA analysis will not be used to select pacing lead location in this study.
The patient will then receive the left ventricular pacing lead in the standard manner.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Standard implantation for cardiac resynchronization ICD or PM implantation
- •Cardiomyopathy with LVEF <35%
- •QRS duration greater than 120 msec
排除标准
- •Age less than 18 years
研究组 & 干预措施
Coronary Sinus Branch Pacing
After cannulation, pacing impulses will be delivered via a Biotronik Vision Guidewire to 3 sites (apical, mid ventricular, and basal) within each coronary sinus branch receiving venous blood from the anterior, lateral and posterior regions of the ventricle.
ECG signals will be saved digitally for analysis
干预措施: Biotronik Vision Guidewire (Device)
结局指标
主要结局
QRS Frequency at Each Paced Location
时间窗: Baseline
Time frequency analysis performed at each location
次要结局
未报告次要终点